SCHEMBL8376232

SCHEMBL8376232

CCCCCCCCNCC(O)CCCCCCCCC(N)=O

nearest known ligand 0.51

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 2/20 0.51
FFAR1 O14842 2/20 0.51
FAAH O00519 3/20 0.47
ANPEP P15144 1/20 0.46
ERAP2 Q6P179 1/20 0.46
GPR84 Q9NQS5 5/20 0.45
SOAT1 P35610 2/20 0.45
MEN1 O00255 1/20 0.45
TP53 P04637 1/20 0.45
CYP1A2 P05177 1/20 0.45
CYP3A4 P08684 1/20 0.45
CYP2C19 P33261 1/20 0.45
KMT2A Q03164 1/20 0.45
NFKB1 P19838 1/20 0.42
EPHX2 P34913 1/20 0.42
KDM4E B2RXH2 2/20 0.41
GNAI3 P08754 1/20 0.40
GNAO1 P09471 1/20 0.40
GNAI1 P63096 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29150180 0.88 FFAR4 (0.70) FFAR4FFAR1FAAHGPR84MEN1
SCHEMBL9063816 0.88 FFAR4 (0.70) FFAR4FFAR1FAAHGPR84MEN1
SCHEMBL1270839 0.87 ANPEP (0.49) FFAR4FFAR1FAAHANPEPERAP2
SCHEMBL17199795 0.87 ANPEP (0.49) FFAR4FFAR1FAAHANPEPERAP2
SCHEMBL1270926 0.87 ANPEP (0.49) FFAR4FFAR1FAAHANPEPERAP2
SCHEMBL11523051 0.87 ANPEP (0.49) FFAR4FFAR1FAAHANPEPERAP2
SCHEMBL11677240 0.87 ANPEP (0.49) FFAR4FFAR1FAAHANPEPERAP2
SCHEMBL6118647 0.87 ANPEP (0.49) FFAR4FFAR1FAAHANPEPERAP2
SCHEMBL13833063 0.87 ANPEP (0.49) FFAR4FFAR1FAAHANPEPERAP2
SCHEMBL16859680 0.87 ANPEP (0.49) FFAR4FFAR1FAAHANPEPERAP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5929081-A ADMINISTERING COMPOUND THAT INHIBITS SIGNAL TRANSDUCTION THROUGH CELLULAR ACCUMULATION OF NON-ARACHIDONYL PHOSPHATIDIC ACID CELL THERAPEUTICS INC. (US) 1999-07-27 US disclosed
US-5859018-A ANTIARTHRITIC AGENTS; ANTITUMOR AGENTS; CARDIOVASCULAR DISORDERS CELL THERAPEUTICS, INC. (US) 1999-01-12 US disclosed
US-5856331-A LYSOPHOSPHATIDIC ACYLTRANSFERASE INHIBITOR CELL THERAPEUTICS, INC. (US) 1999-01-05 US disclosed
US-5795898-A ANTITUMOR, ANTICANCER AGENTS, ANTIDIABETIC AGENTS, SKIN DISORDERS CELL THERAPEUTICS, INC. (US) 1998-08-18 US disclosed
EP-0719267-A1 SECOND MESSENGER CELL SIGNALING INHIBITORS CELL THERAPEUTICS, INC. (US) 1996-07-03 EP disclosed
EP-0719267-A4 SECOND MESSENGER CELL SIGNALING INHIBITORS CELL THERAPEUTICS INC (US) 1996-02-16 EP disclosed
US-5470878-A Cell signaling inhibitors CELL THERAPEUTICS, INC. (US) 1995-11-28 US disclosed
WO-1994022863-A9 SECOND MESSENGER CELL SIGNALING INHIBITORS 1994-12-22 WO disclosed
WO-1994022863-A1 SECOND MESSENGER CELL SIGNALING INHIBITORS CELL THERAPEUTICS, INC. (US) 1994-10-13 WO disclosed