Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1744236 | 0.83 | CYP2C19 (0.31) | — | |
| SCHEMBL14127769 | 0.81 | CETP (0.33) | CPB2 | |
| SCHEMBL3153596 | 0.75 | — | — | |
| SCHEMBL6386232 | 0.75 | CETP (0.33) | CPB2 | |
| SCHEMBL17696860 | 0.75 | MME (0.44) | — | |
| SCHEMBL4706256 | 0.74 | CYP2C19 (0.31) | — | |
| SCHEMBL2923075 | 0.74 | CYP2C19 (0.56) | — | |
| Hydrochloric Acid SCHEMBL11613521 | 0.73 | CYP2C19 (0.38) | CPB2 | |
| SCHEMBL4277564 | 0.71 | CYP2C19 (0.52) | — | |
| SCHEMBL4580987 | 0.71 | CYP2C19 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3068785-A1 | SUBSTITUTED 4,5,6,7-TETRAHYDROPYRAZOLO[1,5-A]PYRAZINE DERIVATIVES AS CASEIN KINASE 1 D/E INHIBITORS | Bristol-Myers Squibb Company (US) | 2016-09-21 | — | — | EP | disclosed |
| EP-2958921-A1 | PYRROLO [2, 3 -D]PYRIMIDINE DERIVATIVES AS INHIBITORS OF JANUS- RELATED KINASES (JAK) | Pfizer Inc. (US) | 2015-12-30 | — | — | EP | disclosed |
| WO-2015073763-A1 | SUBSTITUTED 4,5,6,7-TETRAHYDROPYRAZOLO[1,5-A]PYRAZINE DERIVATIVES AS CASEIN KINASE 1 D/E INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2015-05-21 | — | — | WO | disclosed |
| WO-2014128591-A1 | PYRROLO [2, 3 -D]PYRIMIDINE DERIVATIVES AS INHIBITORS OF JANUS- RELATED KINASES (JAK) | PFIZER INC. (US) | 2014-08-28 | — | — | WO | disclosed |
| WO-1999031048-A1 | FUNGICIDAL AMIDES | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) | 1999-06-24 | — | — | WO | disclosed |