SCHEMBL8377116

SCHEMBL8377116

O=S(=O)(O)CCCCCI

nearest known ligand 0.48

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.48
PTGS1 P23219 1/20 0.39
PDE4A P27815 1/20 0.39
LMNA P02545 1/20 0.39
SLC6A6 P31641 1/20 0.39
CYP2C19 P33261 1/20 0.39
BLM P54132 1/20 0.39
EPHX2 P34913 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8379607 1.00 APP (0.48) APPPTGS1PDE4ALMNASLC6A6
SCHEMBL1001331 0.97
SCHEMBL10706734 0.94 APP (0.48) APPPTGS1PDE4ALMNASLC6A6
SCHEMBL261859 0.88
SCHEMBL3895529 0.86
SCHEMBL6692218 0.85 APP (0.61) APPPTGS1PDE4ALMNASLC6A6
SCHEMBL1270406 0.85 APP (0.61) APPPTGS1PDE4ALMNASLC6A6
SCHEMBL1270542 0.85 APP (0.61) APPPTGS1PDE4ALMNASLC6A6
SCHEMBL563945 0.85 APP (0.61) APPPTGS1PDE4ALMNASLC6A6
SCHEMBL922126 0.85 APP (0.61) APPPTGS1PDE4ALMNASLC6A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5986042-A Cross-linked polymer MITSUI CHEMICALS, INC. (JP) 1999-11-16 US disclosed
EP-0856539-A1 Cross-linked polymer Mitsui Chemicals, Inc. (JP) 1998-08-05 EP disclosed