Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | THPO | P40225 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | GNPAT | O15228 | 2/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | PRNP | P04156 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9187897 | 1.00 | MAPT (0.52) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL7421944 | 0.82 | MAPT (0.53) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL12064024 | 0.82 | MAPT (0.53) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL12064023 | 0.82 | MAPT (0.53) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL4611563 | 0.82 | MAPT (0.53) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL12064254 | 0.82 | MAPT (0.53) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL714056 | 0.82 | MAPT (0.53) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL11732508 | 0.78 | MAPT (0.57) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL11984630 | 0.78 | MAPT (0.57) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL10719696 | 0.77 | MAPT (0.47) | MAPTKDM4ETHRBALOX15NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0673432-B1 | PROCESS FOR PREPARING CLAVULANIC ACID | SMITHKLINE BEECHAM PLC (GB) | 1999-03-24 | — | — | EP | disclosed |
| US-5869299-A | USING AN ENZYME SYSTEM FROM STREPTOMYCES, PARTICULARLY S. CLAVULIGERUS. | SMITHKLINE BEECHAM P.L.C. (GB) | 1999-02-09 | — | — | US | disclosed |
| EP-0673432-A1 | PROCESS FOR PREPARING CLAVULANIC ACID | SMITHKLINE BEECHAM PLC (GB) | 1995-09-27 | — | — | EP | disclosed |
| WO-1994012654-A1 | PROCESS FOR PREPARING CLAVULANIC ACID | SMITHKLINE BEECHAM PLC (GB) | 1994-06-09 | — | — | WO | disclosed |