Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 6/20 | 0.40 |
| ▸ | CA2 | P00918 | 6/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA4 | P22748 | 3/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | EPOR | P19235 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9160309 | 0.91 | HPGD (0.46) | LMNACA1CA2CA12CA9 | |
| SCHEMBL9172385 | 0.89 | HPGD (0.46) | LMNACA1CA2CA12CA9 | |
| SCHEMBL6047708 | 0.87 | EPOR (0.40) | FOLH1CA1CA2CA12CA9 | |
| SCHEMBL6047694 | 0.85 | EPOR (0.40) | FOLH1CA1CA2CA12CA9 | |
| SCHEMBL9164952 | 0.85 | CA1 (0.52) | CA1CA2CA12CA9CA4 | |
| SCHEMBL2597563 | 0.83 | TDP1 (0.42) | LMNATSHRCA1CA2CA4 | |
| SCHEMBL3108023 | 0.83 | TDP1 (0.42) | LMNATSHRCA1CA2CA4 | |
| SCHEMBL2999347 | 0.83 | TDP1 (0.42) | LMNATSHRCA1CA2CA4 | |
| SCHEMBL9166812 | 0.82 | CA1 (0.49) | CA1CA2CA12CA9CA4 | |
| SCHEMBL13527700 | 0.79 | HDAC1 (0.42) | FOLH1CA1CA2CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5859214-A | DTPA monoamides, pharmaceutical agents containing these compounds, their use and process for their production | SCHERING AKTIENGESELLSHAFT (DE) | 1999-01-12 | — | — | US | disclosed |