⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL83854 | 0.92 | — | — | |
| SCHEMBL1656821 | 0.89 | TSHR (0.40) | — | |
| SCHEMBL9801623 | 0.89 | TSHR (0.40) | — | |
| SCHEMBL9801696 | 0.89 | TSHR (0.40) | — | |
| SCHEMBL9801164 | 0.89 | TSHR (0.40) | — | |
| SCHEMBL22500171 | 0.89 | TSHR (0.40) | — | |
| SCHEMBL2268704 | 0.88 | — | — | |
| SCHEMBL9113389 | 0.86 | TSHR (0.48) | — | |
| SCHEMBL4145778 | 0.84 | — | — | |
| SCHEMBL3936494 | 0.83 | TSHR (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 169 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109999036-A | For treating the antiandrogen of non-metastatic castration-resistant prostate cancer | 阿拉贡药品公司 | 2019-07-12 | — | — | CN | claimed |
| CN-109937038-A | Dicyclic nitrogen-containing heterocycle compound | 田边三菱制药株式会社 | 2019-06-25 | — | — | CN | claimed |
| CN-109908114-A | For treating the antiandrogen of non-metastatic castration-resistant prostate cancer | 阿拉贡药品公司 | 2019-06-21 | — | — | CN | claimed |
| CN-106414689-A | Perfume composition | 奇华顿股份有限公司 | 2017-02-15 | — | — | CN | claimed |
| CN-103857667-A | Composition, synthesis and application of hydantoin derivatives | CHEN DEGUI | 2014-06-11 | — | — | CN | claimed |
| WO-1995011899-A1 | PYRIMIDINE DERIVATIVES | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 1995-05-04 | — | — | WO | claimed |
| US-20240226132-A1 | RNA COMPOSITIONS COMPRISING A BUFFER SUBSTANCE AND METHODS FOR PREPARING, STORING AND USING THE SAME | BIONTECH DELIVERY TECHNOLOGIES GMBH (DE) | 2024-07-11 | — | — | US | disclosed |
| WO-2024133635-A1 | COMPOSITION | BIONTECH DELIVERY TECHNOLOGIES GMBH (DE) | 2024-06-27 | — | — | WO | disclosed |
| CN-118201905-A | Cationic lipid | 武田药品工业株式会社 | 2024-06-14 | — | — | CN | disclosed |
| US-20240191009-A1 | POLYFUNCTIONALIZED HIGH-CIS 1,4-POLYBUTADIENE AND METHOD FOR MANUFACTURING THE SAME | KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) | 2024-06-13 | — | — | US | disclosed |
| CN-117615752-A | RNA compositions comprising buffer substances and methods of making, storing, and using the same | 生物技术欧洲股份公司 | 2024-02-27 | — | — | CN | disclosed |
| WO-2024028325-A1 | NUCLEIC ACID COMPOSITIONS COMPRISING AMPHIPHILIC OLIGO ETHYLENE GLYCOL (OEG)-CONJUGATED COMPOUNDS AND METHODS OF USING SUCH COMPOUNDS AND COMPOSITIONS | BioNTech SE (DE) | 2024-02-08 | — | — | WO | disclosed |
| US-20240033344-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING PARTICLES AND MRNA AND METHODS FOR PREPARING AND STORING THE SAME | BioNTech SE (DE) | 2024-02-01 | — | — | US | disclosed |
| US-4760141-A | Hydrocarbyl(polyphenol)-poly(2,2,6,6-tetramethyl piperidyl-1,3,5-triazines) as stabilizers for synthetic polymer compositions | ADEKA ARGUS CHEMICAL CO., LTD. (JP) | 1988-07-26 | — | — | US | disclosed |
| US-4759871-A | Stabilizing the polymer from deterioration upon exposure to light and heat | ADEKA ARGUS CHEMICAL CO., LTD. (JP) | 1988-07-26 | — | — | US | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| US-4740544-A | Hydrocarbyl(polyphenol)-poly(2,2,6,6-tetramethyl piperidyl-1,3,5-triazines) as stabilizers for synthetic polymer compositions | ADEKA ARGUS CHEMICAL CO., LTD. (JP) | 1988-04-26 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |
| EP-0209126-A2 | Hydrocarbyl(polyphenol)-poly(2,2,6,6-tetramethyl piperidyl-1,3,5-triazines) as stabilizers for synthetic polymer compositions | ADEKA ARGUS CHEMICAL CO., Ltd. (JP) | 1987-01-21 | — | — | EP | disclosed |
| US-3996193-A | POLYALKYLENEPOLYAMINES, DIOLEFIN RUBBER | THE DOW CHEMICAL COMPANY (US) | 1976-12-07 | — | — | US | disclosed |