SCHEMBL8379166

SCHEMBL8379166

CC(C)([C]=O)CCN

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1267928 0.75
SCHEMBL270059 0.73
SCHEMBL15332723 0.73
SCHEMBL2128339 0.71
SCHEMBL4322403 0.71
SCHEMBL5456349 0.71
SCHEMBL1410618 0.69
SCHEMBL11568044 0.67
SCHEMBL10581854 0.67
SCHEMBL732717 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3836971-A1 CONJUGATES AND METHODS OF USING THE SAME Flagship Pioneering Innovations V, Inc. (US) 2021-06-23 EP claimed
US-20210162057-A1 CONJUGATES AND METHODS OF USING THE SAME FLAGSHIP PIONEERING INNOVATIONS V, INC. 2021-06-03 US claimed
WO-2020037009-A1 CONJUGATES AND METHODS OF USING THE SAME FLAGSHIP PIONEERING INNOVATIONS V, INC. (US) 2020-02-20 WO claimed
EP-0761678-B1 Fluorine-containing anthracycline derivatives having hydroxyl group(s) mono- or di-o-aminoalkanoylated in the sugar moiety thereof ZAIDAN HOJIN BISEIBUTSU (JP) 1999-03-31 EP claimed
US-5789386-A WATER SOLUBLE ANTITUMOR AGENTS; INJECTABLE ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) 1998-08-04 US claimed
EP-0761678-A1 Fluorine-containing anthracycline derivatives having hydroxyl group(s) mono- or di-o-aminoalkanoylated in the sugar moiety thereof ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) 1997-03-12 EP claimed
CN-115572257-B Synthesis method of pyridone compound 江西帝劢药业有限公司 2024-07-09 CN disclosed
US-11998610-B2 Conjugates and methods of using the same FLAGSHIP PIONEERING INNOVATIONS V, INC. (US) 2024-06-04 US disclosed
EP-3836971-A1 CONJUGATES AND METHODS OF USING THE SAME Flagship Pioneering Innovations V, Inc. (US) 2021-06-23 EP disclosed
US-20210162057-A1 CONJUGATES AND METHODS OF USING THE SAME FLAGSHIP PIONEERING INNOVATIONS V, INC. 2021-06-03 US disclosed
WO-2020037009-A1 CONJUGATES AND METHODS OF USING THE SAME FLAGSHIP PIONEERING INNOVATIONS V, INC. (US) 2020-02-20 WO disclosed
EP-0761678-B1 Fluorine-containing anthracycline derivatives having hydroxyl group(s) mono- or di-o-aminoalkanoylated in the sugar moiety thereof ZAIDAN HOJIN BISEIBUTSU (JP) 1999-03-31 EP disclosed
US-5789386-A WATER SOLUBLE ANTITUMOR AGENTS; INJECTABLE ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) 1998-08-04 US disclosed
EP-0761678-A1 Fluorine-containing anthracycline derivatives having hydroxyl group(s) mono- or di-o-aminoalkanoylated in the sugar moiety thereof ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) 1997-03-12 EP disclosed