Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | NPC1 | O15118 | 6/20 | 0.46 |
| ▸ | RAB9A | P51151 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | MIF | P14174 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.41 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8379854 | 0.92 | SMN1; SMN2 (0.53) | MAPTNPC1RAB9AMIFKMT2A | |
| SCHEMBL8379597 | 0.84 | GAA (0.38) | MAPTKDM4ERECQLALDH1A1HTT | |
| SCHEMBL8379608 | 0.84 | GAA (0.38) | MAPTKDM4ERECQLALDH1A1HTT | |
| SCHEMBL8382792 | 0.82 | MAPT (0.55) | MAPTNPC1RAB9AKDM4EMIF | |
| SCHEMBL8650067 | 0.81 | MAPT (0.50) | MAPTNPC1RAB9AKDM4EMIF | |
| Formic Acid SCHEMBL8381303 | 0.80 | GAA (0.42) | MAPTKDM4ESMN1; SMN2RECQLALDH1A1 | |
| SCHEMBL8379116 | 0.78 | MAPT (0.63) | MAPTNPC1RAB9AKDM4EMIF | |
| SCHEMBL8381490 | 0.78 | MAPT (0.48) | MAPTNPC1RAB9AKDM4EMIF | |
| SCHEMBL8379851 | 0.77 | GAA (0.42) | MAPTKDM4ERECQLALDH1A1HTT | |
| SCHEMBL8382726 | 0.75 | GAA (0.44) | MAPTKDM4ERECQLALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5973188-A | Acetic acid derivatives | HOFFMANN-LA ROCHE INC. (US) | 1999-10-26 | — | — | US | disclosed |