Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F3 | P13726 | 6/20 | 0.44 |
| ▸ | F7 | P08709 | 4/20 | 0.44 |
| ▸ | PLG | P00747 | 5/20 | 0.42 |
| ▸ | PLAU | P00749 | 5/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 9/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 3/20 | 0.37 |
| ▸ | PLAT | P00750 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6774708 | 0.87 | TTR (0.42) | F3F7PLAUF10F2 | |
| SCHEMBL8336242 | 0.84 | F7 (0.41) | F3F7PLGPLAUF10 | |
| SCHEMBL6578738 | 0.72 | MRGPRX4 (0.43) | F3F7F10KDM4E | |
| SCHEMBL5581363 | 0.69 | PLAU (0.69) | F3F7PLGPLAUPLAT | |
| SCHEMBL7919800 | 0.66 | KDM4E (0.64) | KDM4E | |
| SCHEMBL6578909 | 0.66 | F10 (0.65) | F10F2 | |
| SCHEMBL6581914 | 0.65 | F10 (0.61) | F10F2 | |
| SCHEMBL6576600 | 0.65 | F10 (0.60) | F3F7F10F2 | |
| SCHEMBL7406187 | 0.64 | F7 (0.57) | F3F7F10F2 | |
| SCHEMBL6576302 | 0.64 | F10 (0.58) | F3F7F10F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5889005-A | Benzamidine derivatives and their use for treating thrombotic diseases | BERLEX LABORATORIES, INC. (US) | 1999-03-30 | — | — | US | disclosed |
| US-5877181-A | Benzamidine derivatives and their use as anti-coagulants | BERLEX LABORATORIES, INC. (US) | 1999-03-02 | — | — | US | disclosed |