SCHEMBL8380212

SCHEMBL8380212

CCO[Si](OCC)(OCC)c1ccc(C(=O)O)cc1

nearest known ligand 0.53

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.53
MAPT P10636 2/20 0.51
ALDH1A1 P00352 2/20 0.48
TSHR P16473 3/20 0.46
TP53 P04637 2/20 0.46
PLA2G4B P0C869 2/20 0.46
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.43
RXRA P19793 3/20 0.41
RXRB P28702 3/20 0.41
SRD5A2 P31213 1/20 0.41
KMT2A Q03164 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2480326 0.85 MAPT (0.45) HPGDMAPTALDH1A1SMN1; SMN2KMT2A
SCHEMBL2480099 0.84 ELANE (0.50) HPGDMAPTALDH1A1SMN1; SMN2SRD5A2
SCHEMBL23530285 0.83 PARP10 (0.55) ALDH1A1TSHRCA1CA2SMN1; SMN2
SCHEMBL1673163 0.81 CA1 (0.59) HPGDMAPTALDH1A1TSHRCA1
SCHEMBL20478197 0.81 NQO1 (0.35)
SCHEMBL50701 0.81 NQO1 (0.35)
SCHEMBL961674 0.80 MAPT (0.53) MAPTALDH1A1CA1CA2KMT2A
SCHEMBL23493428 0.78 MAPT (0.38) MAPTKMT2A
SCHEMBL4882555 0.78 HPGD (0.59) HPGDALDH1A1TSHRTP53CA1
SCHEMBL5487877 0.77 MAPT (0.33) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6001739-A Method of manufacturing a semiconductor device TOKYO ELECTRON LIMITED (JP) 1999-12-14 US disclosed