Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 2/20 | 0.45 |
| ▸ | AKR1B10 | O60218 | 3/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.42 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.42 |
| ▸ | GABRP | O00591 | 2/20 | 0.41 |
| ▸ | GABRD | O14764 | 2/20 | 0.41 |
| ▸ | G6PD | P11413 | 2/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.41 |
| ▸ | GABRE | P78334 | 2/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.41 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.41 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8014771 | 1.00 | SRD5A2 (0.45) | SRD5A2AKR1B10AKR1B1GPBAR1GABRP | |
| SCHEMBL518237 | 0.88 | SRD5A2 (0.46) | SRD5A2AKR1B10AKR1B1GABRPGABRD | |
| SCHEMBL518238 | 0.88 | SRD5A2 (0.46) | SRD5A2AKR1B10AKR1B1GABRPGABRD | |
| SCHEMBL3869935 | 0.80 | SRD5A1 (0.38) | SRD5A2KMT2A | |
| SCHEMBL15121547 | 0.80 | SRD5A1 (0.38) | SRD5A2KMT2A | |
| SCHEMBL3869928 | 0.80 | SRD5A1 (0.38) | SRD5A2KMT2A | |
| SCHEMBL9665450 | 0.79 | SRD5A2 (0.51) | SRD5A2LMNABLMCYP3A4MAPK1 | |
| SCHEMBL9665439 | 0.79 | SRD5A2 (0.51) | SRD5A2LMNABLMCYP3A4MAPK1 | |
| SCHEMBL9853139 | 0.78 | SRD5A2 (0.40) | SRD5A2 | |
| SCHEMBL4608726 | 0.78 | SRD5A2 (0.72) | SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0902790-A1 | PROCESS FOR PREPARING STEROIDS HAVING A CARBOXAMIDE SIDE-CHAIN | PHARMACIA & UPJOHN S.p.A. (IT) | 1999-03-24 | — | — | EP | claimed |
| WO-1997040062-A1 | PROCESS FOR PREPARING STEROIDS HAVING A CARBOXAMIDE SIDE-CHAIN | PHARMACIA & UPJOHN S.P.A. (IT) | 1997-10-30 | — | — | WO | claimed |