Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.57 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CDC25B | P30305 | 2/20 | 0.50 |
| ▸ | CDC25A | P30304 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6014019 | 0.88 | AKR1C3 (0.71) | KDM4EAKR1C3CYP2C8CYP2C9CDC25B | |
| SCHEMBL30549431 | 0.88 | AKR1C3 (0.71) | KDM4EAKR1C3CYP2C8CYP2C9CDC25B | |
| SCHEMBL6056968 | 0.88 | AKR1C3 (0.71) | KDM4EAKR1C3CYP2C8CYP2C9CDC25B | |
| SCHEMBL15793780 | 0.88 | AKR1C3 (0.71) | KDM4EAKR1C3CYP2C8CYP2C9CDC25B | |
| SCHEMBL7821719 | 0.79 | KDM4E (0.63) | KDM4EAKR1C3CYP2C8CYP2C9CDC25B | |
| SCHEMBL8380470 | 0.78 | TSHR (0.50) | KDM4EAKR1C3CYP2C8CYP2C9HSD17B10 | |
| SCHEMBL20757754 | 0.78 | AKR1C3 (0.62) | KDM4EAKR1C3CYP2C8CYP2C9CDC25B | |
| SCHEMBL8380031 | 0.78 | KDM4E (0.58) | KDM4EAKR1C3CYP2C8CYP2C9CDC25B | |
| SCHEMBL8785619 | 0.77 | KDM4E (0.61) | KDM4EAKR1C3CYP2C8CYP2C9CDC25B | |
| SCHEMBL8784827 | 0.77 | KDM4E (0.61) | KDM4EAKR1C3CYP2C8CYP2C9CDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0713502-B1 | NAPHTHALENEDICARBOXYLIC ACID CONTAINING POLYMER/HALOGEN COMPOUND COMPOSITIONS HAVING REDUCED FLUORESCENCE | EASTMAN CHEM CO (US) | 1999-04-07 | — | — | EP | claimed |
| EP-0713502-A1 | NAPHTHALENEDICARBOXYLIC ACID CONTAINING POLYMER/HALOGEN COMPOUND COMPOSITIONS HAVING REDUCED FLUORESCENCE | EASTMAN CHEMICAL COMPANY (US) | 1996-05-29 | — | — | EP | claimed |
| US-5391701-A | Containing difunctional aromatic monomer having at least one halogen group directly attached to ring | EASTMAN CHEMICAL COMPANY (US) | 1995-02-21 | — | — | US | claimed |
| WO-1995004769-A1 | NAPHTHALENEDICARBOXYLIC ACID CONTAINING POLYMER/HALOGEN COMPOUND COMPOSITIONS HAVING REDUCED FLUORESCENCE | EASTMAN CHEMICAL COMPANY (US) | 1995-02-16 | — | — | WO | claimed |
| EP-0713506-B1 | A PROCESS FOR PREPARING POLY(ETHYLENE 2,6-NAPHTHALENEDICARBOXYLATE) CONTAINING POLYMER BLENDS HAVING REDUCED FLUORESCENCE | EASTMAN CHEM CO (US) | 1997-05-07 | — | — | EP | disclosed |
| US-5391702-A | Melt blending with a fluorescence-quenching aromatic ketone or aromatic alcohol and forming | EASTMAN CHEMICAL COMPANY (US) | 1995-02-21 | — | — | US | disclosed |
| US-5391330-A | Melt blending aromatic ketone or naphthol compounds | EASTMAN CHEMICAL COMPANY (US) | 1995-02-21 | — | — | US | disclosed |