Benzamide

Benzamide

SCHEMBL8380567

NC(=O)c1ccccc1.O=C(CCC1CCCCC1)OO

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.53
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
SMN1; SMN2 Q16637 2/20 0.51
ALDH1A1 P00352 1/20 0.51
NPC1 O15118 1/20 0.51
RAB9A P51151 1/20 0.51
PARP15 Q460N3 2/20 0.50
PARP10 Q53GL7 2/20 0.50
KLK7 P49862 2/20 0.50
MAPT P10636 4/20 0.49
TDP1 Q9NUW8 2/20 0.49
MIF P14174 1/20 0.49
POLB P06746 1/20 0.46
CYP3A4 P08684 1/20 0.46
PARP1 P09874 1/20 0.46
TSHR P16473 1/20 0.46
CYP2C19 P33261 1/20 0.46
RECQL P46063 1/20 0.46
BLM P54132 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9004410 0.81 HPGD (0.50) MEN1KMT2ASMN1; SMN2ALDH1A1NPC1
SCHEMBL7651380 0.79 HPGD (0.47) MEN1KMT2ASMN1; SMN2ALDH1A1KLK7
SCHEMBL5787921 0.78 KLK7 (0.53) L3MBTL1MEN1KMT2ASMN1; SMN2ALDH1A1
SCHEMBL2443481 0.77 KMT2A (0.68) L3MBTL1MEN1KMT2ASMN1; SMN2ALDH1A1
SCHEMBL13912376 0.77 KMT2A (0.68) L3MBTL1MEN1KMT2ASMN1; SMN2ALDH1A1
SCHEMBL27821337 0.76 HPGD (0.56) L3MBTL1MEN1KMT2ASMN1; SMN2ALDH1A1
SCHEMBL28946798 0.75 KMT2A (0.69) L3MBTL1MEN1KMT2ASMN1; SMN2ALDH1A1
Biphenyl SCHEMBL27833272 0.74 POLB (0.64) L3MBTL1NPC1RAB9APARP15PARP10
SCHEMBL28006498 0.74 KLK7 (0.56) L3MBTL1MEN1KMT2ASMN1; SMN2ALDH1A1
Benzamide SCHEMBL7761457 0.74 PARP1 (0.84) L3MBTL1ALDH1A1PARP10MAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0734377-B1 PERCARBOXYLIC ACIDS SOLVAY INTEROX LTD (GB) 1999-08-25 EP disclosed
US-5914303-A FOR BLEACHING, WASHING, DISINFECTING SOLVAY INTEROX LIMITED (GB) 1999-06-22 US disclosed