⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14283394 | 0.70 | — | — | |
| SCHEMBL8026239 | 0.70 | — | — | |
| SCHEMBL8800727 | 0.67 | — | — | |
| SCHEMBL7039373 | 0.65 | — | — | |
| SCHEMBL31132603 | 0.64 | P4HTM (0.42) | — | |
| SCHEMBL7016950 | 0.64 | — | — | |
| Hydrochloric Acid SCHEMBL5023483 | 0.61 | MEN1 (0.41) | — | |
| SCHEMBL4906133 | 0.61 | KMT2A (0.36) | — | |
| SCHEMBL11883930 | 0.60 | — | — | |
| SCHEMBL9457578 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118103048-A | Treatment of tumors with NK cells and EGFR-targeting antibodies | 埃迪瓦生物治疗公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-117529327-A | Treatment of tumors with NK cells and antibodies targeting CD20 | 埃迪瓦生物治疗公司 | 2024-02-06 | — | — | CN | disclosed |
| US-8901119-B2 | Peptide deformylase inhibitors | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO. 2) LIMITED (GB) | 2014-12-02 | — | — | US | disclosed |
| EP-2684039-A2 | PEPTIDE DEFORMYLASE INHIBITORS | Glaxosmithkline Intellectual Property (No. 2) Limited (GB) | 2014-01-15 | — | — | EP | disclosed |
| US-20130345120-A1 | PEPTIDE DEFORMYLASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2013-12-26 | — | — | US | disclosed |
| WO-2012122450-A2 | PEPTIDE DEFORMYLASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2012-09-13 | — | — | WO | disclosed |
| US-8143396-B2 | 1-[2′, 3′ -dideoxy-3′ C- (hydroxymethyl)—beta-D-erythro-pentofuranosyl] cytosine derivatives as HIV inhibitors | MEDIVIR AB (SE) | 2012-03-27 | — | — | US | disclosed |
| EP-1899352-B1 | 1- [2' , 3' -DIDEOXY-3' C- (HYDROXYMETHYL) - BETA-D-ERYTHRO-PENTOFURANOSYL] CYTOSINE DERIVATIVES AS HIV INHIBITORS | MEDIVIR AB (SE) | 2011-10-05 | — | — | EP | disclosed |
| EP-2336135-A2 | 1-[2',3'-dideoxy-3'c-(hydroxymethyl)- beta-d-erythro-pentofuranosyl]cytosine derivatives as HIV inhibitors | Medivir AB (SE) | 2011-06-22 | — | — | EP | disclosed |
| US-20110112294-A1 | 1-[2', 3' -DIDEOXY-3' C- (HYDROXYMETHYL) - BETA-D-ERYTHRO-PENTOFURANOSYL] CYTOSINE DERIVATIVES AS HIV INHIBITORS | MEDIVIR AB (SE) | 2011-05-12 | — | — | US | disclosed |
| US-6348457-B1 | ANTAGONIZING RESERPINE IN MAMMALS | JANSSEN PHARMACEUTICA N.V. (BE) | 2002-02-19 | — | — | US | disclosed |
| EP-0672043-B1 | NOVEL 4-(3-BENZOFURANYL)PIPERIDINYL AND 4-(3-BENZOTHIENYL)PIPERIDINYL DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | JANSSEN PHARMACEUTICA NV (BE) | 2001-05-30 | — | — | EP | disclosed |
| US-6232375-B1 | POLYVINYL CHLORIDE | WITCO VINYL ADDITIVES GMBH (DE) | 2001-05-15 | — | — | US | disclosed |
| US-6232375-B1 | POLYVINYL CHLORIDE | WITCO VINYL ADDITIVES GMBH (DE) | 2001-05-15 | — | — | US | disclosed |
| EP-1083912-A1 | ANTITHROMBOTIC AGENTS | ROWETT RESEARCH SERVICES LIMITED (GB) | 2001-03-21 | — | — | EP | disclosed |
| EP-1044968-A1 | 6-Amino-2-(thi)oxo-pyrimidin-4-one and 7-amino- 2,3-dihydrooxazolo[2,3-b]pyrimidin-5-one derivatives, their preparation and their use as stabilisers for halogen-containing polymers | Witco Vinyl Additives GmbH (DE) | 2000-10-18 | — | — | EP | disclosed |
| EP-1044968-A1 | 6-Amino-2-(thi)oxo-pyrimidin-4-one and 7-amino- 2,3-dihydrooxazolo[2,3-b]pyrimidin-5-one derivatives, their preparation and their use as stabilisers for halogen-containing polymers | Witco Vinyl Additives GmbH (DE) | 2000-10-18 | — | — | EP | disclosed |
| WO-1999055350-A1 | ANTITHROMBOTIC AGENTS | ROWETT RESEARCH SERVICES LIMITED (GB) | 1999-11-04 | — | — | WO | disclosed |
| EP-0672043-A1 | NOVEL 4-(3-BENZOFURANYL)PIPERIDINYL AND 4-(3-BENZOTHIENYL)PIPERIDINYL DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | JANSSEN PHARMACEUTICA N.V. (BE) | 1995-09-20 | — | — | EP | disclosed |
| WO-1994001437-A1 | NOVEL 4-(3-BENZOFURANYL)PIPERIDINYL AND 4-(3-BENZOTHIENYL)PIPERIDINYL DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | JANSSEN PHARMACEUTICA N.V. (BE) | 1994-01-20 | — | — | WO | disclosed |