⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8380665 | 1.00 | — | — | |
| SCHEMBL107995 | 0.75 | TSHR (0.38) | — | |
| SCHEMBL107996 | 0.75 | TSHR (0.38) | — | |
| SCHEMBL2180945 | 0.74 | — | — | |
| SCHEMBL3642469 | 0.72 | — | — | |
| SCHEMBL1783355 | 0.72 | — | — | |
| SCHEMBL3642472 | 0.72 | — | — | |
| SCHEMBL286698 | 0.72 | — | — | |
| SCHEMBL19054898 | 0.72 | — | — | |
| SCHEMBL14614685 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705827-B1 | Interleukin-1 inhibiting manumycin derivatives and streptomyces strains for their production | KYOWA HAKKO KOGYO KK (JP) | 1999-03-31 | — | — | EP | claimed |
| US-5804599-A | OXABICYCLO(4.1.0)HEPTANE DERIVATIVES; ANTIBACTERIAL AGENTS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1998-09-08 | — | — | US | claimed |
| EP-0705827-B1 | Interleukin-1 inhibiting manumycin derivatives and streptomyces strains for their production | KYOWA HAKKO KOGYO KK (JP) | 1999-03-31 | — | — | EP | disclosed |
| US-5804599-A | OXABICYCLO(4.1.0)HEPTANE DERIVATIVES; ANTIBACTERIAL AGENTS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1998-09-08 | — | — | US | disclosed |
| US-5804599-A | OXABICYCLO(4.1.0)HEPTANE DERIVATIVES; ANTIBACTERIAL AGENTS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1998-09-08 | — | — | US | disclosed |