Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.38 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 2/20 | 0.35 |
| ▸ | NOS1 | P29475 | 2/20 | 0.35 |
| ▸ | NOS2 | P35228 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8380716 | 1.00 | MAPK1 (0.44) | MAPK1MEN1KMT2ACYP2C9LMNA | |
| SCHEMBL10348014 | 0.99 | MAPK1 (0.43) | MAPK1MEN1KMT2ACYP2C9LMNA | |
| SCHEMBL10419638 | 0.96 | MEN1 (0.41) | MAPK1MEN1KMT2ACYP2C9LMNA | |
| SCHEMBL10347915 | 0.96 | MEN1 (0.41) | MAPK1MEN1KMT2ACYP2C9LMNA | |
| SCHEMBL10347923 | 0.96 | MEN1 (0.41) | MAPK1MEN1KMT2ACYP2C9LMNA | |
| SCHEMBL10348631 | 0.96 | MEN1 (0.41) | MAPK1MEN1KMT2ACYP2C9LMNA | |
| SCHEMBL8377172 | 0.96 | MEN1 (0.43) | MAPK1MEN1KMT2ACYP2C9LMNA | |
| SCHEMBL8377174 | 0.96 | MEN1 (0.43) | MAPK1MEN1KMT2ACYP2C9LMNA | |
| SCHEMBL3761250 | 0.94 | MEN1 (0.42) | MAPK1MEN1KMT2ACYP2C9LMNA | |
| SCHEMBL10348016 | 0.94 | MEN1 (0.42) | MAPK1MEN1KMT2ACYP2C9LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958290-A | ELECTROOPTICAL APPARATUS WITH DIELECTRIC LIQUID CRYSTALS FOR RADIATION TRANSPARENT MEDIUM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1999-09-28 | — | — | US | disclosed |
| US-5344587-A | Nitriles | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1994-09-06 | — | — | US | disclosed |
| EP-0272580-B1 | Liquidcrystalline cyclohexylbenzene derivatives their manufacturing and novel nematic admixtures containing same | WOJSKOWA AKAD TECH (PL) | 1994-08-17 | — | — | EP | disclosed |
| WO-1991005029-A1 | ELECTRO-OPTICAL LIQUID CRYSTAL SYSTEM | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1991-04-18 | — | — | WO | disclosed |