Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 9/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | RARA | P10276 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | MTOR | P42345 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | PLA2G1B | P04054 | 3/20 | 0.47 |
| ▸ | ATG4B | Q9Y4P1 | 3/20 | 0.47 |
| ▸ | THRA | P10827 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8376557 | 0.94 | RARB (0.70) | RARBMEN1ALDH1A1RARAMAPT | |
| SCHEMBL8378009 | 0.94 | RARB (0.70) | RARBMEN1ALDH1A1RARAMAPT | |
| SCHEMBL11590735 | 0.91 | TP53 (0.56) | RARBMEN1ALDH1A1RARAMAPT | |
| SCHEMBL2231026 | 0.91 | TP53 (0.56) | RARBMEN1ALDH1A1RARAMAPT | |
| SCHEMBL959756 | 0.89 | RARB (0.53) | RARBMEN1ALDH1A1RARAMAPT | |
| SCHEMBL14288441 | 0.86 | TP53 (0.51) | RARBMEN1ALDH1A1RARAMAPT | |
| SCHEMBL2433670 | 0.85 | HSD17B3 (0.53) | RARBMEN1ALDH1A1RARAMAPT | |
| SCHEMBL11590781 | 0.84 | RARB (0.51) | RARBMEN1ALDH1A1RARAMAPT | |
| SCHEMBL18979307 | 0.81 | RARB (0.90) | RARBMEN1ALDH1A1RARAMAPT | |
| SCHEMBL503506 | 0.81 | RARB (0.90) | RARBMEN1ALDH1A1RARAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958290-A | ELECTROOPTICAL APPARATUS WITH DIELECTRIC LIQUID CRYSTALS FOR RADIATION TRANSPARENT MEDIUM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1999-09-28 | — | — | US | disclosed |
| US-5344587-A | Nitriles | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1994-09-06 | — | — | US | disclosed |