Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MGAM | O43451 | 1/20 | 0.45 |
| ▸ | SI | P14410 | 1/20 | 0.45 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.45 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | TNKS | O95271 | 2/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.41 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.40 |
| ▸ | GCGR | P47871 | 1/20 | 0.40 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.40 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19350079 | 0.85 | MAPK1 (0.49) | MAPK1GAAMGAMSIMGAM2 | |
| SCHEMBL8380776 | 0.83 | MAPK1 (0.47) | MAPK1GAAMGAMSIMGAM2 | |
| Hydrochloric Acid SCHEMBL8963881 | 0.83 | MAPK1 (0.47) | MAPK1GAAMGAMSIMGAM2 | |
| SCHEMBL23736192 | 0.82 | HEXA (0.47) | MAPK1GAAMGAMSIMGAM2 | |
| Hydrochloric Acid SCHEMBL1436191 | 0.82 | MAPK1 (0.46) | MAPK1GAAMGAMSIMGAM2 | |
| SCHEMBL11601324 | 0.80 | MAPK1 (0.44) | MAPK1GAAMGAMSIMGAM2 | |
| SCHEMBL11861194 | 0.77 | MAPK1 (0.49) | MAPK1GAAMGAMSIMGAM2 | |
| SCHEMBL23758268 | 0.77 | MAPK1 (0.54) | MAPK1GAAMGAMSIMGAM2 | |
| Hydrochloric Acid SCHEMBL10646858 | 0.76 | MAPK1 (0.41) | MAPK1GAAMGAMSIMGAM2 | |
| Hydrochloric Acid SCHEMBL11602991 | 0.76 | MAPK1 (0.41) | MAPK1GAAMGAMSIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5945425-A | ADENOSINE TRIPHOSPHASE INHIBITOR; DNA VIRICIDE | G.D. SEARLE & CO. (US) | 1999-08-31 | — | — | US | claimed |