Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8382819 | 1.00 | DPP4 (0.46) | DPP4EPHX1TDP1L3MBTL1POLB | |
| SCHEMBL8381130 | 1.00 | DPP4 (0.46) | DPP4EPHX1TDP1L3MBTL1POLB | |
| SCHEMBL3502622 | 0.85 | CYP2D6 (0.48) | DPP4TDP1L3MBTL1CYP2C19CYP2D6 | |
| SCHEMBL8383523 | 0.85 | CYP2D6 (0.48) | DPP4TDP1L3MBTL1CYP2C19CYP2D6 | |
| SCHEMBL8382398 | 0.85 | CYP2D6 (0.48) | DPP4TDP1L3MBTL1CYP2C19CYP2D6 | |
| SCHEMBL3502623 | 0.85 | CYP2D6 (0.48) | DPP4TDP1L3MBTL1CYP2C19CYP2D6 | |
| SCHEMBL18165397 | 0.85 | CYP2D6 (0.48) | DPP4TDP1L3MBTL1CYP2C19CYP2D6 | |
| Hydrochloric Acid SCHEMBL7386141 | 0.83 | CYP2D6 (0.46) | DPP4TDP1L3MBTL1CYP2D6SRC | |
| SCHEMBL3611836 | 0.78 | DPP4 (0.50) | DPP4EPHX1CYP2D6SRCF2 | |
| SCHEMBL15577857 | 0.78 | DPP4 (0.50) | DPP4EPHX1CYP2D6SRCF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0425212-B1 | Cyclic anti-aggregatory peptides | SMITHKLINE BEECHAM CORP (US) | 1999-04-07 | — | — | EP | disclosed |