Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL838014 | 0.94 | GCK (0.58) | GCKKCNH2 | |
| SCHEMBL838013 | 0.94 | GCK (0.58) | GCKKCNH2 | |
| SCHEMBL3303999 | 0.91 | GCK (0.55) | GCKKCNH2 | |
| SCHEMBL839882 | 0.84 | GCK (0.70) | GCKKCNH2 | |
| SCHEMBL839109 | 0.84 | GCK (0.77) | GCKKCNH2 | |
| SCHEMBL838721 | 0.83 | GCK (0.71) | GCKKCNH2 | |
| SCHEMBL838665 | 0.82 | GCK (0.73) | GCKKCNH2 | |
| SCHEMBL839662 | 0.81 | GCK (0.61) | GCKKCNH2 | |
| SCHEMBL839661 | 0.81 | GCK (0.61) | GCKKCNH2 | |
| SCHEMBL839200 | 0.81 | GCK (0.61) | GCKKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143263-B2 | Therapeutic agents | ASTRAZENECA AB (SE) | 2012-03-27 | — | — | US | disclosed |