Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL838212 | 0.87 | GCK (0.45) | GCKKCNH2 | |
| SCHEMBL839158 | 0.83 | GCK (0.76) | GCKKCNH2 | |
| SCHEMBL3125949 | 0.83 | GCK (0.76) | GCKKCNH2 | |
| SCHEMBL839614 | 0.80 | GCK (0.65) | GCKKCNH2 | |
| SCHEMBL839615 | 0.80 | GCK (0.65) | GCKKCNH2 | |
| SCHEMBL840029 | 0.79 | GCK (0.40) | GCKKCNH2 | |
| SCHEMBL839761 | 0.79 | GCK (0.78) | GCKKCNH2 | |
| SCHEMBL840175 | 0.79 | GCK (0.78) | GCKKCNH2 | |
| SCHEMBL839762 | 0.79 | GCK (0.78) | GCKKCNH2 | |
| SCHEMBL838663 | 0.79 | GCK (0.78) | GCKKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143263-B2 | Therapeutic agents | ASTRAZENECA AB (SE) | 2012-03-27 | — | — | US | disclosed |