SCHEMBL8387145

SCHEMBL8387145

CCCCCCCCOc1ccc(C(=O)Nc2ccc(O)cc2)cc1OCCCCCCCC

nearest known ligand 0.66

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 3/20 0.66
SMPD1 P17405 6/20 0.60
LMNA P02545 1/20 0.57
MAPT P10636 1/20 0.57
CNR1 P21554 2/20 0.55
HDAC3 O15379 1/20 0.52
HDAC1 Q13547 1/20 0.52
HDAC2 Q92769 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8388370 0.93 CNR2 (0.60) CNR2SMPD1MAPTCNR1
SCHEMBL8391512 0.93 CNR2 (0.60) CNR2SMPD1MAPTCNR1
SCHEMBL8756745 0.88 CNR2 (0.55) CNR2SMPD1LMNAMAPTCNR1
SCHEMBL8757152 0.85 MCHR1 (0.53) CNR2SMPD1MAPTCNR1
SCHEMBL8391501 0.84 POLB (0.56) CNR2MAPT
SCHEMBL8757069 0.83 SMN1; SMN2 (0.67) LMNAMAPT
SCHEMBL8390958 0.83 SMN1; SMN2 (0.67) LMNAMAPT
SCHEMBL8756930 0.83 SMN1; SMN2 (0.67) LMNAMAPT
SCHEMBL8390939 0.83 SMN1; SMN2 (0.67) LMNAMAPT
SCHEMBL11250057 0.83 SMPD1 (0.65) SMPD1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6004899-A SURFACE TREATED WITH SILANE, TITANATE, AND/OR ALUMINUM COUPLING AGENT; PIGMENT; ERASIBILITY MITSUBISHI PAPER MILLS LIMITED (JP) 1999-12-21 US disclosed
EP-0574879-B1 Reversible heat-sensitive recording material MITSUBISHI PAPER MILLS LTD (JP) 1997-05-02 EP disclosed
US-5395815-A Phenolic compound electron acceptor; images; contrast; stability MITSUBISHI PAPER MILLS LIMITED (JP) 1995-03-07 US disclosed
EP-0574879-A1 Reversible heat-sensitive recording material MITSUBISHI PAPER MILLS, LTD. (JP) 1993-12-22 EP disclosed