SCHEMBL8387339

SCHEMBL8387339

CC(C)(C)[C@@H]1CCC[C@@H](O)C1

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.36
CNR2 P34972 15/20 0.36
LMNA P02545 1/20 0.32
CYP2C9 P11712 1/20 0.32
EPHX1 P07099 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8390236 1.00 TSHR (0.36) TSHRCNR2LMNACYP2C9EPHX1
SCHEMBL636500 1.00 TSHR (0.36) TSHRCNR2LMNACYP2C9EPHX1
SCHEMBL22252171 1.00 TSHR (0.36) TSHRCNR2LMNACYP2C9EPHX1
SCHEMBL13154335 1.00 TSHR (0.36) TSHRCNR2LMNACYP2C9EPHX1
SCHEMBL18634343 1.00 TSHR (0.36) TSHRCNR2LMNACYP2C9EPHX1
SCHEMBL4845508 0.95 TSHR (0.43) TSHRCNR2LMNACYP2C9EPHX1
SCHEMBL4845193 0.93 TSHR (0.41) TSHRCNR2LMNACYP2C9EPHX1
SCHEMBL9847170 0.85 TSHR (0.36) TSHRCNR2LMNACYP2C9
SCHEMBL7753132 0.84 SLC18A3 (0.38) LMNACYP2C9EPHX1
SCHEMBL10236414 0.84 SLC18A3 (0.38) LMNACYP2C9EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0612840-B1 Cyclic compounds and their use as perfuming ingredients GIVAUDAN ROURE INT (CH) 1999-05-06 EP disclosed
US-5525589-A ODORANT COMPOSITIONS GIVAUDAN-ROURE CORPORATION (US) 1996-06-11 US disclosed
EP-0612840-A2 Cyclic compounds and their use as perfuming ingredients GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) 1994-08-31 EP disclosed