Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNK2 | Q07912 | 4/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 12/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 2/20 | 0.42 |
| ▸ | MAPK13 | O15264 | 3/20 | 0.42 |
| ▸ | MAPK12 | P53778 | 3/20 | 0.42 |
| ▸ | MAPK11 | Q15759 | 3/20 | 0.42 |
| ▸ | GCGR | P47871 | 2/20 | 0.42 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.40 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8390603 | 1.00 | TNK2 (0.46) | TNK2MAPK14ALOX5DHODHMAPK13 | |
| SCHEMBL8309777 | 0.88 | MAPK14 (0.49) | TNK2MAPK14ALOX5DHODHMAPK13 | |
| SCHEMBL8310271 | 0.88 | MAPK14 (0.49) | TNK2MAPK14ALOX5DHODHMAPK13 | |
| SCHEMBL3306458 | 0.83 | MAPK14 (0.44) | MAPK14ALOX5MAPK13MAPK12MAPK11 | |
| SCHEMBL14838246 | 0.81 | CKS1B (0.46) | TNK2 | |
| SCHEMBL4980350 | 0.72 | HMGCR (0.48) | — | |
| SCHEMBL4980355 | 0.72 | HMGCR (0.48) | — | |
| SCHEMBL27793218 | 0.70 | MAPK14 (0.48) | MAPK14ALOX5MAPK13MAPK12MAPK11 | |
| SCHEMBL23410401 | 0.69 | GRIA1 (0.53) | MAPK14GRIA1 | |
| SCHEMBL6643926 | 0.68 | MAPK14 (0.60) | MAPK14MAPK13MAPK12MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955480-A | GLUCAGON RECEPTOR ANTAGONISTS, CYTOKINE INHIBITORS | MERCK & CO., INC. (US) | 1999-09-21 | — | — | US | disclosed |