Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | GRIK1 | P39086 | 8/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GRIK2 | Q13002 | 5/20 | 0.38 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.38 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.38 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.38 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.38 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | KISS1R | Q969F8 | 2/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8778828 | 1.00 | KDM4E (0.48) | KDM4ETSHRGRIK1ALDH1A1TDP1 | |
| SCHEMBL3627155 | 0.98 | KDM4E (0.50) | KDM4ETSHRGRIK1ALDH1A1TDP1 | |
| SCHEMBL3627154 | 0.98 | KDM4E (0.50) | KDM4ETSHRGRIK1ALDH1A1TDP1 | |
| SCHEMBL7700265 | 0.98 | KDM4E (0.50) | KDM4ETSHRGRIK1ALDH1A1TDP1 | |
| SCHEMBL10937503 | 0.82 | KDM4E (0.48) | KDM4ETSHRGRIK1GRIK2GRIA2 | |
| SCHEMBL10937515 | 0.82 | KDM4E (0.48) | KDM4ETSHRGRIK1GRIK2GRIA2 | |
| SCHEMBL11802504 | 0.82 | KDM4E (0.48) | KDM4ETSHRGRIK1GRIK2GRIA2 | |
| SCHEMBL11748378 | 0.81 | KDM4E (0.43) | KDM4ETSHRGRIK1ALDH1A1TDP1 | |
| SCHEMBL11746585 | 0.80 | KDM4E (0.46) | KDM4ETSHRGRIK1GRIK2GRIA2 | |
| SCHEMBL9363963 | 0.80 | GRIK1 (0.43) | GRIK1ALDH1A1TDP1GRIK2GRIA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0605105-B1 | Process for rigid foams | ICI PLC (GB) | 1999-05-06 | — | — | EP | disclosed |
| US-5393799-A | Reacting reaction product of excess polyisocyanate and fluorinated isocyanate-reactive compound with polyfunctional reactive composition under foam-forming conditions | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1995-02-28 | — | — | US | disclosed |
| EP-0605105-A1 | Process for rigid foams | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-07-06 | — | — | EP | disclosed |