Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 2/20 | 0.48 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.48 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.48 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.48 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.48 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.43 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.43 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.43 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.43 |
| ▸ | ARG1 | P05089 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27150371 | 1.00 | GRIN2D (0.48) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL2783482 | 0.83 | GRIN2D (0.60) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL9179307 | 0.83 | GRIN2D (0.60) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL1662284 | 0.83 | GRIN2D (0.60) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL1807296 | 0.83 | GRIA1 (0.53) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL6493867 | 0.83 | GRIA1 (0.53) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL3182737 | 0.83 | GRIA1 (0.53) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL1811917 | 0.83 | GRIA1 (0.53) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL13319977 | 0.83 | GRIA1 (0.53) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL839398 | 0.80 | GRIN2D (0.41) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5880138-A | ANTAGONISTS OF EXCITATORY AMINO ACIDS | ELI LILLY AND COMPANY (US) | 1999-03-09 | — | — | US | claimed |
| US-20240238207-A1 | Encased Tamper Resistant Controlled Release Dosage Forms | PURDUE PHARMA LP (US) | 2024-07-18 | — | — | US | disclosed |
| US-20230301921-A1 | Encased Tamper Resistant Controlled Release Dosage Forms | PURDUE PHARMA L.P. | 2023-09-28 | — | — | US | disclosed |
| US-11590082-B2 | Encased tamper resistant controlled release dosage forms | PURDUE PHARMA L.P. (US) | 2023-02-28 | — | — | US | disclosed |
| US-20210251907-A1 | Encased Tamper Resistant Controlled Release Dosage Forms | PURDUE PHARMA L.P. | 2021-08-19 | — | — | US | disclosed |
| US-10966932-B2 | Encased tamper resistant controlled release dosage forms | PURDUE PHARMA L.P. (US) | 2021-04-06 | — | — | US | disclosed |
| US-20200121608-A1 | Encased Tamper Resistant Controlled Release Dosage Forms | PURDUE PHARMA LP (US) | 2020-04-23 | — | — | US | disclosed |
| US-20190022086-A1 | CONTROLLED RELEASE HYDROCODONE FORMULATIONS | PURDUE PHARMA LP (US) | 2019-01-24 | — | — | US | disclosed |
| US-10179130-B2 | Controlled release hydrocodone formulations | PURDUE PHARMA L.P. (US) | 2019-01-15 | — | — | US | disclosed |
| US-10076516-B2 | Methods of manufacturing oral dosage forms | PURDUE PHARMA L.P. (US) | 2018-09-18 | — | — | US | disclosed |
| US-6733783-B2 | Controlled release hydrocodone formulations | EURO-CELTIQUE S.A. (LU) | 2004-05-11 | — | — | US | disclosed |
| US-20040047907-A1 | Controlled release hydrocodone formulations | PURDUE PHARMA L.P. | 2004-03-11 | — | — | US | disclosed |
| EP-1337244-A1 | CONTROLLED RELEASE HYDROCODONE FORMULATIONS | Euroceltique S.A. (LU) | 2003-08-27 | — | — | EP | disclosed |
| US-20020192277-A1 | Controlled release hydrocodone formulations | PURDUE PHARMA L.P. | 2002-12-19 | — | — | US | disclosed |
| EP-1227798-A1 | CONTROLLED RELEASE HYDROCODONE FORMULATIONS | Euro-Celtique S.A. (LU) | 2002-08-07 | — | — | EP | disclosed |
| WO-2002036099-A1 | CONTROLLED RELEASE HYDROCODONE FORMULATIONS | EURO-CELTIQUE S.A. (LU) | 2002-05-10 | — | — | WO | disclosed |
| WO-2000018378-A9 | SUSTAINED RELEASE HYDROMORPHONE FORMULATIONS EXHIBITING BIMODAL CHARACTERISTICS | EURO CELTIQUE SA (LU) | 2001-07-19 | — | — | WO | disclosed |
| WO-2001032148-A1 | CONTROLLED RELEASE HYDROCODONE FORMULATIONS | EURO-CELTIQUE, S.A. (LU) | 2001-05-10 | — | — | WO | disclosed |
| WO-2000018378-A1 | SUSTAINED RELEASE HYDROMORPHONE FORMULATIONS EXHIBITING BIMODAL CHARACTERISTICS | EURO-CELTIQUE, S.A. (LU) | 2000-04-06 | — | — | WO | disclosed |
| US-5880138-A | ANTAGONISTS OF EXCITATORY AMINO ACIDS | ELI LILLY AND COMPANY (US) | 1999-03-09 | — | — | US | disclosed |