Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ERCC5 | P28715 | 2/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8390497 | 0.91 | NPSR1 (0.50) | NPSR1MAPTLMNAL3MBTL1S1PR3 | |
| SCHEMBL9056373 | 0.86 | ELANE (0.57) | MAPTLMNAS1PR3MEN1KMT2A | |
| SCHEMBL8389023 | 0.85 | CYP3A4 (0.49) | MAPTS1PR3MEN1KMT2AELANE | |
| SCHEMBL8390685 | 0.82 | DYRK1A (0.50) | S1PR3ELANEMAOB | |
| SCHEMBL8390500 | 0.82 | MAPT (0.58) | NPSR1MAPTLMNAL3MBTL1MEN1 | |
| SCHEMBL8388916 | 0.81 | KDM4E (0.54) | NPSR1MAPTLMNAL3MBTL1MEN1 | |
| SCHEMBL8387038 | 0.81 | KMT2A (0.54) | MAPTLMNAL3MBTL1MEN1KMT2A | |
| SCHEMBL8391192 | 0.81 | S1PR3 (0.49) | MAPTS1PR3MEN1KMT2AELANE | |
| SCHEMBL9056683 | 0.80 | NPSR1 (0.64) | NPSR1MAPTLMNAL3MBTL1MEN1 | |
| SCHEMBL8389101 | 0.79 | DYRK1A (0.52) | L3MBTL1S1PR3ELANEMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5877199-A | ALZHEIMER'S DISEASE; SEDATIVE | SANKYO COMPANY, LIMITED (JP) | 1999-03-02 | — | — | US | disclosed |
| WO-1996003377-A1 | HETEROCYCLIC COMPOUNDS, USEFUL AS ALLOSTERIC EFFECTORS AT MUSCARINIC RECEPTORS | SANKYO COMPANY, LIMITED (JP) | 1996-02-08 | — | — | WO | disclosed |