SCHEMBL8391

SCHEMBL8391

[CH2]C[Si](C)(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6156566 0.74
SCHEMBL5574015 0.70
SCHEMBL4917125 0.70
SCHEMBL9692439 0.70
SCHEMBL5400988 0.67
SCHEMBL7705696 0.67
SCHEMBL33463 0.67
SCHEMBL560152 0.67
SCHEMBL7130475 0.65
SCHEMBL7133188 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 21201 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110799520-B Method for synthesizing peptides containing N-substituted amino acids 中外制药株式会社 2024-07-12 CN claimed
WO-2024140934-A1 PREPARATION METHOD FOR LINKER-DRUG CONJUGATE AND INTERMEDIATE THEREOF 上海复旦张江生物医药股份有限公司 2024-07-04 WO claimed
CN-118281320-A Lithium ion battery electrolyte matched with high-nickel ternary cathode material-silicon-based anode material and lithium ion battery 深圳市研一新材料有限责任公司 2024-07-02 CN claimed
CN-118281321-A Lithium ion battery electrolyte matched with high-nickel ternary cathode material and lithium ion battery 深圳市研一新材料有限责任公司 2024-07-02 CN claimed
CN-118281333-A Electrolyte additive, nonaqueous electrolyte and application thereof 深圳市研一新材料有限责任公司 2024-07-02 CN claimed
CN-118221644-A Pyrrolidine derivative, composition and application thereof 上海京新生物医药有限公司 2024-06-21 CN claimed
WO-2024114776-A1 BICYCLIC ABASIC NUCLEIC ACID ANALOGS AND OLIGOMERIC COMPOUNDS PREPARED THEREFROM 上海舶望制药有限公司 2024-06-06 WO claimed
WO-2024110477-A2 SYNTHESIS OF A CYCLIC PEPTIDE JANSSEN PHARMACEUTICA NV (BE) 2024-05-30 WO claimed
US-20240158446-A1 CYCLIC COMPOUND HAVING SELECTIVE INHIBITORY ACTION ON KRAS OVER HRAS AND NRAS CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2024-05-16 US claimed
WO-2024089310-A1 BIODEGRADABLE IMINOSUGARS AND AMINO CYCLITOL GLYCOSIDES INHIBITING ALPHA-GLUCOSIDASE WITH SYNERGISTIC INSECTICIDE OR ACARICIDE ACTIVITY OR BOTH FRANCISCO ARAGÓN S.L.U (ES) 2024-05-02 WO claimed
EP-0053541-B1 OXACEPHALOSPORINS AND THEIR PREPARATION RHONE-POULENC SANTE (FR) 1985-02-13 EP claimed
US-4481049-A UNSATURATED ESTER CONTAINING SILICON AT&T BELL LABORATORIES (US) 1984-11-06 US claimed
EP-0053072-B1 OXACEPHALOSPORINS AND THEIR PREPARATION RHONE-POULENC SANTE (FR) 1984-08-08 EP claimed
US-4440779-A Tricyclic derivatives of substituted pyrrole acids as analgesic and anti-inflammatory agents MERCK & CO., INC. (US) 1984-04-03 US claimed
EP-0102239-A1 Azetidinone derivatives, a process for their preparation and their use as intermediates in the preparation of carbapenem antibiotics SANKYO COMPANY LIMITED (JP) 1984-03-07 EP claimed
EP-0010347-B1 NOVEL SUBSTITUTED OMEGA-AROYL(PROPIONYL OR BUTYRYL)-L-PROLINES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESSES FOR THEIR PREPARATION AMERICAN CYANAMID COMPANY (US) 1983-11-09 EP claimed
US-4370478-A Oxacephalosporins RHONE-POULENC INDUSTRIES (FR) 1983-01-25 US claimed
US-4369315-A ANTIBIOTIC RHONE-POULENC INDUSTRIES (FR) 1983-01-18 US claimed
US-4369314-A Oxacephalosporins RHONE-POULENC INDUSTRIES (FR) 1983-01-18 US claimed
EP-0010347-A1 Novel substituted omega-aroyl(propionyl or butyryl)-L-prolines, pharmaceutical compositions containing them and processes for their preparation AMERICAN CYANAMID COMPANY (US) 1980-04-30 EP claimed