Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.67 |
| ▸ | RAB9A | P51151 | 2/20 | 0.67 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.67 |
| ▸ | JAK2 | O60674 | 1/20 | 0.67 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.53 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | TP53 | P04637 | 3/20 | 0.52 |
| ▸ | GPX4 | P36969 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | TACR1 | P25103 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15269042 | 1.00 | NPC1 (0.67) | NPC1RAB9APAX8JAK2CHRM2 | |
| SCHEMBL15271897 | 1.00 | NPC1 (0.67) | NPC1RAB9APAX8JAK2CHRM2 | |
| SCHEMBL15269110 | 1.00 | NPC1 (0.67) | NPC1RAB9APAX8JAK2CHRM2 | |
| SCHEMBL8393246 | 0.98 | NPC1 (0.64) | NPC1RAB9APAX8JAK2CHRM2 | |
| SCHEMBL6780126 | 0.94 | NPC1 (0.57) | NPC1RAB9APAX8JAK2CHRM2 | |
| SCHEMBL15269078 | 0.92 | NPC1 (0.58) | NPC1RAB9APAX8JAK2CHRM2 | |
| SCHEMBL15269082 | 0.92 | NPC1 (0.58) | NPC1RAB9APAX8JAK2CHRM2 | |
| SCHEMBL27983244 | 0.88 | NPC1 (0.59) | NPC1RAB9APAX8JAK2CHRM2 | |
| SCHEMBL9711647 | 0.87 | SMN1; SMN2 (0.58) | NPC1RAB9APAX8JAK2CHRM2 | |
| SCHEMBL6002892 | 0.86 | NPC1 (0.64) | NPC1RAB9APAX8JAK2CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0752414-B1 | Process for the production of aromatic urethanes | MINI RICERCA SCIENT TECNOLOG (IT) | 1999-05-06 | — | — | EP | disclosed |
| US-5688988-A | REACTION OF AN ORGANIC CARBONATE WITH AROMATIC AMINE USING A ZINC AND/OR COPPER CARBONATE HYDROXIDE CATALYST | MINISTERO DELL'UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECHNOLOGICA (IT) | 1997-11-18 | — | — | US | disclosed |
| EP-0752414-A1 | Process for the production of aromatic urethanes | MINISTERO DELL' UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECNOLOGICA (IT) | 1997-01-08 | — | — | EP | disclosed |
| EP-0027940-B2 | PROCESS FOR PREPARING URETHANES | BAYER AG (DE) | 1986-12-30 | — | — | EP | disclosed |
| EP-0027940-B1 | PROCESS FOR PREPARING URETHANES | BAYER AG (DE) | 1983-09-14 | — | — | EP | disclosed |
| EP-0027954-B1 | PROCESS FOR PREPARING URETHANES AND THEIR USE IN THE PREPARATION OF ISOCYANATES | BAYER AG (DE) | 1982-11-24 | — | — | EP | disclosed |
| EP-0027940-A1 | Process for preparing urethanes | BAYER AG (DE) | 1981-05-06 | — | — | EP | disclosed |
| EP-0027954-A1 | Process for preparing urethanes and their use in the preparation of isocyanates | BAYER AG (DE) | 1981-05-06 | — | — | EP | disclosed |