Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 2/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.40 |
| ▸ | MGLL | Q99685 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 2/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8392342 | 1.00 | GBA1 (0.45) | GBA1S1PR1PTGS1PTGS2MGLL | |
| SCHEMBL10337488 | 0.92 | DPP4 (0.40) | GBA1S1PR1ALDH1A1BCHEACHE | |
| SCHEMBL31093244 | 0.90 | GBA1 (0.47) | GBA1S1PR1PTGS1PTGS2MGLL | |
| SCHEMBL9769185 | 0.90 | GBA1 (0.47) | GBA1S1PR1PTGS1PTGS2MGLL | |
| SCHEMBL9769271 | 0.90 | GBA1 (0.47) | GBA1S1PR1PTGS1PTGS2MGLL | |
| SCHEMBL9617015 | 0.90 | GBA1 (0.47) | GBA1S1PR1PTGS1PTGS2MGLL | |
| SCHEMBL31093212 | 0.90 | GBA1 (0.47) | GBA1S1PR1PTGS1PTGS2MGLL | |
| SCHEMBL4421172 | 0.88 | GBA1 (0.44) | GBA1S1PR1PTGS1PTGS2MGLL | |
| SCHEMBL8392265 | 0.86 | GBA1 (0.45) | GBA1S1PR1PTGS1PTGS2MGLL | |
| SCHEMBL10582154 | 0.85 | DPP4 (0.38) | GBA1S1PR1ALDH1A1ALOX5LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2901297-B2 | — | — | 1999-06-07 | — | — | JP | claimed |
| EP-0378657-A1 | OXAZOLIDINONE PENETRATION ENHANCING COMPOUNDS. | RAJADHYAKSHA VITHAL J | 1990-07-25 | — | — | EP | claimed |
| WO-1990000407-A1 | OXAZOLIDINONE PENETRATION ENHANCING COMPOUNDS | RAJADHYAKSHA VITHAL J (US) | 1990-01-25 | — | — | WO | claimed |
| US-4960771-A | TRANSDERMAL DELIVERY OF THERAPEUTIC AGENTS; DRUGS, SUNSCREENS, INSECT REPELLENTS, COSMETICS | LVMH MOET HENNESSY LOUIS VUITTON, INC. | 1990-10-02 | — | — | US | disclosed |
| EP-0378657-A1 | OXAZOLIDINONE PENETRATION ENHANCING COMPOUNDS. | RAJADHYAKSHA VITHAL J | 1990-07-25 | — | — | EP | disclosed |
| WO-1990000407-A1 | OXAZOLIDINONE PENETRATION ENHANCING COMPOUNDS | RAJADHYAKSHA VITHAL J (US) | 1990-01-25 | — | — | WO | disclosed |