Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNRHR | P30968 | 19/20 | 0.61 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8184930 | 0.79 | GNRHR (0.77) | GNRHRCYP3A4 | |
| SCHEMBL8184205 | 0.79 | GNRHR (0.67) | GNRHRCYP3A4 | |
| SCHEMBL8182738 | 0.77 | GNRHR (0.71) | GNRHRCYP3A4 | |
| SCHEMBL6981043 | 0.76 | GNRHR (0.66) | GNRHRCACNA1BCYP3A4 | |
| SCHEMBL7827210 | 0.74 | CACNA1B (0.64) | GNRHRCACNA1BCYP3A4 | |
| SCHEMBL7903275 | 0.74 | GNRHR (1.00) | GNRHR | |
| SCHEMBL8184838 | 0.74 | GNRHR (0.82) | GNRHR | |
| SCHEMBL8145820 | 0.71 | GNRHR (0.92) | GNRHR | |
| SCHEMBL8393414 | 0.71 | GNRHR (0.60) | GNRHRCACNA1BCYP3A4 | |
| SCHEMBL8020455 | 0.71 | GNRHR (0.67) | GNRHRCACNA1BCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6004984-A | Antagonists of gonadotropin releasing hormone | MERCK & CO., INC. (US) | 1999-12-21 | — | — | US | disclosed |