Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | FPR2 | P25090 | 3/20 | 0.32 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8395002 | 1.00 | KDM1A (0.33) | KDM1AFPR2FGFR2FGFR1SPHK1 | |
| SCHEMBL8831207 | 0.94 | SPHK1 (0.31) | KDM1AFPR2FGFR2FGFR1SPHK1 | |
| SCHEMBL8448414 | 0.94 | SPHK1 (0.31) | KDM1AFPR2FGFR2FGFR1SPHK1 | |
| SCHEMBL8448411 | 0.94 | SPHK1 (0.31) | KDM1AFPR2FGFR2FGFR1SPHK1 | |
| SCHEMBL8521736 | 0.92 | KDM1A (0.34) | KDM1AFPR2FGFR2FGFR1 | |
| SCHEMBL8521738 | 0.92 | KDM1A (0.34) | KDM1AFPR2FGFR2FGFR1 | |
| SCHEMBL8452221 | 0.86 | KDM1A (0.32) | KDM1AFPR2 | |
| SCHEMBL8452220 | 0.86 | KDM1A (0.32) | KDM1AFPR2 | |
| SCHEMBL8831723 | 0.86 | KDM1A (0.32) | KDM1AFPR2 | |
| SCHEMBL8394911 | 0.82 | KDM1A (0.36) | KDM1AFPR2FGFR2FGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5980778-A | STABILITY, COMPATIBILITY | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1999-11-09 | — | — | US | disclosed |
| EP-0650969-B1 | A Silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHINETSU CHEMICAL CO (JP) | 1999-05-26 | — | — | EP | disclosed |
| US-5659059-A | Silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1997-08-19 | — | — | US | disclosed |
| EP-0768361-A1 | Liquid crystal composition and liquid crystal display element comprising the same | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1997-04-16 | — | — | EP | disclosed |
| EP-0650969-A1 | A Silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | Shin-Etsu Chemical Co., Ltd. (JP) | 1995-05-03 | — | — | EP | disclosed |