Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8397162 | 0.90 | EDNRB (0.37) | EDNRBEDNRA | |
| SCHEMBL8395136 | 0.79 | EDNRA (0.51) | EDNRBEDNRA | |
| SCHEMBL7590654 | 0.70 | EDNRA (0.53) | EDNRBEDNRA | |
| SCHEMBL8397158 | 0.69 | EDNRA (0.49) | EDNRBEDNRA | |
| SCHEMBL7596071 | 0.67 | EDNRA (0.52) | EDNRBEDNRA | |
| SCHEMBL7591775 | 0.65 | EDNRB (0.51) | EDNRBEDNRA | |
| SCHEMBL8398732 | 0.65 | EDNRA (0.42) | EDNRBEDNRA | |
| SCHEMBL7591710 | 0.63 | EDNRA (0.56) | EDNRBEDNRA | |
| SCHEMBL8395712 | 0.63 | EDNRB (0.53) | EDNRBEDNRA | |
| SCHEMBL8399583 | 0.63 | EDNRA (0.51) | EDNRBEDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5856484-A | Sulfonylaminopyrimidine carboxylic acid derivatives having endothelin inhibiting activity | HOFFMANN-LA ROCHE INC. (US) | 1999-01-05 | — | — | US | disclosed |