Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8397521 | 0.99 | HRH3 (0.36) | HRH3 | |
| Cipralisant SCHEMBL8395048 | 0.80 | HRH3 (0.57) | HRH3 | |
| Cipralisant SCHEMBL7069804 | 0.80 | HRH3 (0.57) | HRH3 | |
| Cipralisant SCHEMBL7069808 | 0.80 | HRH3 (0.57) | HRH3 | |
| SCHEMBL8397428 | 0.77 | HRH3 (0.37) | HRH3 | |
| SCHEMBL8397507 | 0.73 | HRH3 (0.33) | HRH3 | |
| SCHEMBL7621345 | 0.71 | HRH4 (0.30) | HRH3 | |
| SCHEMBL7621912 | 0.70 | HRH4 (0.32) | HRH3 | |
| SCHEMBL7784064 | 0.68 | CDK1 (0.30) | — | |
| SCHEMBL7787707 | 0.68 | CDK1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6008240-A | AN ANTAGONIST OF HISTAMINE H3 RECEPTORS; FOR TREATING ALLERGY, INFLAMMATION, CARDIOVASCULAR DISEASE (HYPER OR HYPOTENSION), GASTROINTESTINAL DISORDERS, CNS DISORDERS INVOLVING ATTENTION OR COGNITIVE DISORDERS | GLIATECH, INC. (US) | 1999-12-28 | — | — | US | disclosed |