Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8397960 | 0.93 | AKR1B1 (0.41) | AKR1B1LTB4R2MAOAMAOBHDAC6 | |
| SCHEMBL8400340 | 0.92 | AKR1B1 (0.46) | AKR1B1LMNAMAPT | |
| SCHEMBL8399205 | 0.92 | AKR1B1 (0.40) | AKR1B1LMNAPTGDR2HDAC6ALDH1A1 | |
| SCHEMBL8396280 | 0.92 | AKR1B1 (0.40) | AKR1B1LTB4R2HDAC6MAPT | |
| SCHEMBL8396397 | 0.89 | AKR1B1 (0.38) | AKR1B1LTB4R2LMNAMAPT | |
| SCHEMBL8399186 | 0.89 | USP2 (0.40) | AKR1B1LTB4R2LMNAPTGDR2ALDH1A1 | |
| SCHEMBL8400726 | 0.89 | AKR1B1 (0.38) | AKR1B1LMNAHDAC6MAPT | |
| SCHEMBL8398003 | 0.89 | AKR1B1 (0.38) | AKR1B1HDAC6 | |
| SCHEMBL8399142 | 0.88 | AKR1B1 (0.41) | AKR1B1LTB4R2LMNA | |
| SCHEMBL8395772 | 0.87 | SMN1; SMN2 (0.41) | AKR1B1LTB4R2MAOBLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647636-B1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | SENJU PHARMA CO (JP) | 1999-06-09 | — | — | EP | disclosed |
| US-5532257-A | ENZYME INHIBITOR | SENJU PHARMACEUTICAL CO., LTD (JP) | 1996-07-02 | — | — | US | disclosed |
| EP-0647636-A1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Senju Pharmaceutical Co., Ltd. (JP) | 1995-04-12 | — | — | EP | disclosed |