Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.55 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MME | P08473 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8396778 | 0.98 | CYP4F2 (0.53) | CYP4F2CYP4A11NPSR1MAPTP2RX7 | |
| SCHEMBL8392776 | 0.98 | CYP4F2 (0.53) | CYP4F2CYP4A11NPSR1MAPTP2RX7 | |
| SCHEMBL8393649 | 0.96 | CYP4F2 (0.50) | CYP4F2CYP4A11NPSR1MAPTP2RX7 | |
| SCHEMBL8395812 | 0.91 | — | — | |
| SCHEMBL17155 | 0.80 | CYP4F2 (0.56) | CYP4F2CYP4A11NPSR1MAPTP2RX7 | |
| SCHEMBL761603 | 0.80 | CYP4F2 (0.61) | CYP4F2CYP4A11NPSR1MAPTP2RX7 | |
| SCHEMBL8392544 | 0.79 | SMN1; SMN2 (0.38) | CYP4F2CYP4A11MEN1KMT2AALDH1A1 | |
| SCHEMBL1969086 | 0.78 | CYP4F2 (0.55) | CYP4F2CYP4A11NPSR1MAPTP2RX7 | |
| SCHEMBL3541279 | 0.78 | CYP4F2 (0.55) | CYP4F2CYP4A11NPSR1MAPTP2RX7 | |
| SCHEMBL8270187 | 0.78 | CYP4F2 (0.59) | CYP4F2CYP4A11NPSR1MAPTP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5864043-A | CARDIOVASCULAR DISORDERS AND ANGIOTENSIN ANTAGONIST | KARL THOMAE GMBH (DE) | 1999-01-26 | — | — | US | disclosed |
| US-5541229-A | ANGIOITENSIN II ANTAGONIST AS HYPOTENSIVE AGENTS, ANTIISCHEMIC AGENTS AND CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |