Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8042519 | 0.99 | EDNRA (1.00) | EDNRACCR4 | |
| SCHEMBL8395498 | 0.98 | EDNRA (0.98) | EDNRACCR4 | |
| SCHEMBL8391561 | 0.87 | EDNRA (0.79) | EDNRACCR4 | |
| SCHEMBL8054316 | 0.87 | EDNRA (0.98) | EDNRACCR4 | |
| SCHEMBL8055274 | 0.86 | EDNRA (0.78) | EDNRACCR4 | |
| SCHEMBL8393140 | 0.86 | EDNRA (0.77) | EDNRACCR4 | |
| SCHEMBL1387349 | 0.85 | EDNRA (1.00) | EDNRACCR4 | |
| SCHEMBL8391095 | 0.85 | EDNRA (0.76) | EDNRACCR4 | |
| SCHEMBL8054320 | 0.84 | EDNRA (0.98) | EDNRACCR4 | |
| SCHEMBL1731970 | 0.83 | CCR4 (0.74) | EDNRACCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0752986-B1 | N-HETEROCYCLYL SULPHONAMIDE DERIVATIVES AND THEIR USE AS ENDOTHELIN ANTAGONISTS | ZENECA LTD (GB) | 1999-05-19 | — | — | EP | disclosed |