Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.39 |
| ▸ | TP53 | P04637 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | RNF4 | P78317 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8398032 | 0.92 | SMN1; SMN2 (0.44) | SMN1; SMN2TP53LMNATHRBMAPT | |
| SCHEMBL8400414 | 0.92 | SMN1; SMN2 (0.41) | SMN1; SMN2TP53LMNAMAPTMEN1 | |
| SCHEMBL8399636 | 0.90 | SMN1; SMN2 (0.38) | SMN1; SMN2TP53LMNAMAPTGAA | |
| SCHEMBL8396376 | 0.90 | SMN1; SMN2 (0.40) | SMN1; SMN2LMNAMAPTALDH1A1HPGD | |
| SCHEMBL8397981 | 0.90 | SMN1; SMN2 (0.40) | SMN1; SMN2LMNAMAPTALDH1A1HPGD | |
| SCHEMBL8396242 | 0.90 | SMN1; SMN2 (0.52) | SMN1; SMN2TP53MAPTHPGDGAA | |
| SCHEMBL8396279 | 0.90 | USP2 (0.40) | SMN1; SMN2TP53LMNATHRBRNF4 | |
| SCHEMBL8398046 | 0.89 | SMN1; SMN2 (0.39) | SMN1; SMN2TP53LMNAMAPTALDH1A1 | |
| SCHEMBL8400255 | 0.89 | SMN1; SMN2 (0.39) | SMN1; SMN2MAPTMEN1POLBKMT2A | |
| SCHEMBL8396653 | 0.89 | SMN1; SMN2 (0.39) | SMN1; SMN2TP53LMNATHRBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647636-B1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | SENJU PHARMA CO (JP) | 1999-06-09 | — | — | EP | disclosed |
| US-5532257-A | ENZYME INHIBITOR | SENJU PHARMACEUTICAL CO., LTD (JP) | 1996-07-02 | — | — | US | disclosed |
| EP-0647636-A1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Senju Pharmaceutical Co., Ltd. (JP) | 1995-04-12 | — | — | EP | disclosed |