Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.86 |
| ▸ | RAB9A | P51151 | 3/20 | 0.86 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.72 |
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | TSPO | P30536 | 1/20 | 0.53 |
| ▸ | CDK4 | P11802 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7282371 | 0.87 | NPC1 (0.89) | NPC1RAB9AKMT2ACA12CA9 | |
| SCHEMBL4072151 | 0.85 | NPC1 (0.85) | NPC1RAB9AKMT2ACA12CA9 | |
| SCHEMBL5607426 | 0.84 | NPC1 (0.83) | NPC1RAB9AKMT2ACA12CA9 | |
| SCHEMBL11532673 | 0.84 | NPC1 (0.59) | NPC1RAB9AKMT2AALDH1A1POLB | |
| SCHEMBL1690816 | 0.84 | NPC1 (0.82) | NPC1RAB9AKMT2ACA12CA9 | |
| SCHEMBL12290151 | 0.84 | NPC1 (0.82) | NPC1RAB9AKMT2ACA12CA9 | |
| SCHEMBL20954579 | 0.84 | NPC1 (0.82) | NPC1RAB9AKMT2ACA12CA9 | |
| SCHEMBL4064581 | 0.84 | KMT2A (1.00) | NPC1RAB9AKMT2ACA12CA9 | |
| SCHEMBL6403459 | 0.83 | NPC1 (0.59) | NPC1RAB9AKMT2ACA12CA9 | |
| SCHEMBL6403389 | 0.82 | RAB9A (0.79) | NPC1RAB9AKMT2ACA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0748310-B1 | DIESTERS OF CARBONIC ACID ENDOWED WITH ANTIVIRAL AND ANTI-INFLAMMATORY ACTIVITY | ITALFARMACO SPA (IT) | 1999-06-02 | — | — | EP | disclosed |
| US-5827881-A | ADMINISTERING FOR TREATMENT OF VIRAL DISEASES OR AS ANTIINFLAMMATORY AGENTS | ITALFARMACO S.P.A. (IT) | 1998-10-27 | — | — | US | disclosed |
| EP-0748310-A1 | DIESTERS OF CARBONIC ACID ENDOWED WITH ANTIVIRAL AND ANTI-INFLAMMATORY ACTIVITY | ITALFARMACO S.p.A. (IT) | 1996-12-18 | — | — | EP | disclosed |
| WO-1995023128-A1 | DIESTERS OF CARBONIC ACID ENDOWED WITH ANTIVIRAL AND ANTI-INFLAMMATORY ACTIVITY | ITALFARMACO S.P.A. (IT) | 1995-08-31 | — | — | WO | disclosed |