Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.39 |
| ▸ | APP | P05067 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | FASN | P49327 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.31 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.30 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.30 |
| ▸ | RARB | P10826 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8397327 | 1.00 | CYP3A4 (0.39) | CYP3A4APPCYP2C9CYP2C19CYP2D6 | |
| SCHEMBL8397246 | 0.91 | CYP3A4 (0.37) | CYP3A4APPCYP2C9CYP2C19CYP2D6 | |
| SCHEMBL8397245 | 0.91 | CYP3A4 (0.37) | CYP3A4APPCYP2C9CYP2C19CYP2D6 | |
| SCHEMBL8021750 | 0.91 | CYP3A4 (0.36) | CYP3A4APPCYP2C9CYP2C19CYP2D6 | |
| SCHEMBL9008508 | 0.91 | CYP3A4 (0.36) | CYP3A4APPCYP2C9CYP2C19CYP2D6 | |
| SCHEMBL8021747 | 0.91 | CYP3A4 (0.36) | CYP3A4APPCYP2C9CYP2C19CYP2D6 | |
| SCHEMBL8021743 | 0.91 | CYP3A4 (0.36) | CYP3A4APPCYP2C9CYP2C19CYP2D6 | |
| SCHEMBL8951132 | 0.88 | CYP3A4 (0.38) | CYP3A4APPCYP2C9CYP2C19CYP2D6 | |
| SCHEMBL8951125 | 0.88 | CYP3A4 (0.38) | CYP3A4APPCYP2C9CYP2C19CYP2D6 | |
| SCHEMBL7766371 | 0.88 | RARB (0.37) | CYP3A4APPCYP2C9CYP2C19CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0650969-B1 | A Silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHINETSU CHEMICAL CO (JP) | 1999-05-26 | — | — | EP | disclosed |
| US-5659059-A | Silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1997-08-19 | — | — | US | disclosed |
| EP-0650969-A1 | A Silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | Shin-Etsu Chemical Co., Ltd. (JP) | 1995-05-03 | — | — | EP | disclosed |