Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7591775 | 0.93 | EDNRB (0.51) | EDNRBEDNRA | |
| SCHEMBL7594344 | 0.91 | EDNRB (0.63) | EDNRBEDNRA | |
| SCHEMBL7586114 | 0.91 | EDNRA (0.75) | EDNRBEDNRA | |
| SCHEMBL7602383 | 0.90 | EDNRB (0.61) | EDNRBEDNRA | |
| SCHEMBL8395257 | 0.88 | EDNRB (0.61) | EDNRBEDNRA | |
| SCHEMBL8399577 | 0.88 | EDNRA (0.61) | EDNRBEDNRA | |
| SCHEMBL8397142 | 0.87 | EDNRA (0.70) | EDNRBEDNRA | |
| SCHEMBL7584274 | 0.85 | EDNRB (0.62) | EDNRBEDNRA | |
| SCHEMBL7946111 | 0.84 | EDNRA (0.73) | EDNRBEDNRA | |
| SCHEMBL7589737 | 0.83 | EDNRA (0.62) | EDNRBEDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5856484-A | Sulfonylaminopyrimidine carboxylic acid derivatives having endothelin inhibiting activity | HOFFMANN-LA ROCHE INC. (US) | 1999-01-05 | — | — | US | disclosed |