Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 7/20 | 0.48 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PTPRC | P08575 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8399021 | 1.00 | HIF1A (0.48) | HIF1ACAPN1FFAR1KDM4ESMN1; SMN2 | |
| SCHEMBL8399114 | 0.91 | HIF1A (0.42) | HIF1AFFAR1KDM4EMAOB | |
| SCHEMBL8399111 | 0.91 | HIF1A (0.42) | HIF1AFFAR1KDM4EMAOB | |
| SCHEMBL8592174 | 0.90 | HIF1A (0.41) | HIF1AFFAR1KDM4EMAOB | |
| SCHEMBL8396372 | 0.90 | HIF1A (0.41) | HIF1AFFAR1KDM4EMAOB | |
| SCHEMBL7543010 | 0.90 | HIF1A (0.49) | HIF1AFFAR1KDM4EMAOB | |
| SCHEMBL8592175 | 0.90 | HIF1A (0.41) | HIF1AFFAR1KDM4EMAOB | |
| SCHEMBL8396370 | 0.90 | HIF1A (0.41) | HIF1AFFAR1KDM4EMAOB | |
| SCHEMBL8593371 | 0.90 | HIF1A (0.49) | HIF1AFFAR1KDM4EMAOB | |
| SCHEMBL8593728 | 0.89 | HIF1A (0.42) | HIF1AFFAR1KDM4EMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0644183-B1 | Process of producing N-alkylacetamides | SHIONOGI & CO (JP) | 1999-06-02 | — | — | EP | disclosed |
| EP-0658541-B1 | PROCESS FOR PRODUCING CARBOXYLIC ACID DERIVATIVE | SHIONOGI & CO (JP) | 1998-05-20 | — | — | EP | disclosed |
| EP-0658543-B1 | PROCESS FOR PRODUCING ALPHA-ALKOXYIMINOPHENYLACETONITRILE DERIVATIVE | SHIONOGI & CO (JP) | 1998-01-07 | — | — | EP | disclosed |
| US-5510506-A | Process for producing carboxylic acid derivatives | SHIONOGI & CO., LTD. (JP) | 1996-04-23 | — | — | US | disclosed |
| US-5498792-A | Process of producing N-alkylacetamides | SHIONOGI & CO., LTD. (JP) | 1996-03-12 | — | — | US | disclosed |
| EP-0658543-A1 | PROCESS FOR PRODUCING $g(a)-ALKOXYIMINOPHENYLACETONITRILE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1995-06-21 | — | — | EP | disclosed |
| EP-0658541-A1 | PROCESS FOR PRODUCING CARBOXYLIC ACID DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1995-06-21 | — | — | EP | disclosed |