Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 8/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8399101 | 1.00 | HIF1A (0.54) | HIF1AMEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL8621332 | 0.92 | HIF1A (0.60) | HIF1ANPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL8621337 | 0.92 | HIF1A (0.60) | HIF1ANPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL8398990 | 0.90 | HIF1A (0.53) | HIF1AMEN1KMT2AALDH1A1POLB | |
| SCHEMBL8400203 | 0.90 | HIF1A (0.55) | HIF1AMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL8400211 | 0.90 | HIF1A (0.55) | HIF1AMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL8398999 | 0.90 | HIF1A (0.53) | HIF1AMEN1KMT2AALDH1A1POLB | |
| SCHEMBL8369944 | 0.88 | HIF1A (0.56) | HIF1AMEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL8096251 | 0.88 | HIF1A (0.56) | HIF1AMEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL8096246 | 0.88 | HIF1A (0.56) | HIF1AMEN1KMT2ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0644183-B1 | Process of producing N-alkylacetamides | SHIONOGI & CO (JP) | 1999-06-02 | — | — | EP | disclosed |
| US-5498792-A | Process of producing N-alkylacetamides | SHIONOGI & CO., LTD. (JP) | 1996-03-12 | — | — | US | disclosed |
| EP-0644183-A2 | Process of producing N-alkylacetamides | SHIONOGI & CO., LTD. (JP) | 1995-03-22 | — | — | EP | disclosed |