Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY2 | P41231 | 10/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | P2RY6 | Q15077 | 6/20 | 0.55 |
| ▸ | P2RY4 | P51582 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | MTOR | P42345 | 1/20 | 0.53 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.53 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.53 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.53 |
| ▸ | ST6GAL1 | P15907 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11138670 | 0.90 | P2RY2 (0.70) | P2RY2TSHRGLAP2RY6P2RY4 | |
| SCHEMBL597403 | 0.89 | P2RY2 (0.62) | P2RY2TSHRGLAP2RY6P2RY4 | |
| SCHEMBL28272571 | 0.89 | P2RY2 (0.68) | P2RY2TSHRGLAP2RY6P2RY4 | |
| SCHEMBL6402546 | 0.88 | TSHR (0.65) | P2RY2TSHRGLAP2RY6P2RY4 | |
| SCHEMBL8399850 | 0.88 | P2RY2 (0.58) | P2RY2TSHRGLAP2RY6P2RY4 | |
| SCHEMBL4316734 | 0.87 | P2RY2 (0.64) | P2RY2TSHRGLAP2RY6P2RY4 | |
| Cytarabine 5'-Phosphate SCHEMBL28968855 | 0.84 | P2RY2 (0.69) | P2RY2TSHRGLAP2RY6P2RY4 | |
| SCHEMBL7148623 | 0.84 | P2RY2 (0.60) | P2RY2TSHRGLAP2RY6P2RY4 | |
| SCHEMBL14125515 | 0.84 | P2RY2 (0.62) | P2RY2TSHRGLAP2RY6P2RY4 | |
| SCHEMBL154172 | 0.83 | P2RY2 (0.76) | P2RY2P2RY6P2RY4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5872108-A | Reduction of infarct volume using citicoline | INTERNEURON PHARMACEUTICALS, INC. (US) | 1999-02-16 | — | — | US | claimed |
| US-5827832-A | Method of protecting brain tissue from cerebral infarction subsequent to ischemia | INTERNEURON PHARMACEUTICALS, INC. (US) | 1998-10-27 | — | — | US | claimed |
| US-5801160-A | Method of protecting brain tissue from cerebral infarction subsequent to ischemia | INTERNEURON PHARMACEUTICALS, INC. (US) | 1998-09-01 | — | — | US | claimed |
| US-4386078-A | CYTIDINE DIPHOSPHOETHANOLAMINES AND CYTIDINEDIPHOSPHOCHOLINE; STROKE, CARDIOVASCULAR DISEASE, INJURIES | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1983-05-31 | — | — | US | claimed |
| US-4386078-A | CYTIDINE DIPHOSPHOETHANOLAMINES AND CYTIDINEDIPHOSPHOCHOLINE; STROKE, CARDIOVASCULAR DISEASE, INJURIES | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1983-05-31 | — | — | US | disclosed |