Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 8/20 | 0.47 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8400214 | 1.00 | HIF1A (0.47) | HIF1APPARDTP53HTTTHRA | |
| SCHEMBL8397750 | 0.97 | HIF1A (0.46) | HIF1APPARDTHRATHRB | |
| SCHEMBL8397737 | 0.97 | HIF1A (0.46) | HIF1APPARDTHRATHRB | |
| SCHEMBL8397892 | 0.93 | HIF1A (0.48) | HIF1APPARDTP53HTT | |
| SCHEMBL8397885 | 0.93 | HIF1A (0.48) | HIF1APPARDTP53HTT | |
| SCHEMBL8399073 | 0.90 | HIF1A (0.46) | HIF1APPARD | |
| SCHEMBL8399070 | 0.90 | HIF1A (0.46) | HIF1APPARD | |
| SCHEMBL8396069 | 0.90 | HIF1A (0.51) | HIF1ATP53HTT | |
| SCHEMBL8396065 | 0.90 | HIF1A (0.51) | HIF1ATP53HTT | |
| SCHEMBL8399035 | 0.87 | HIF1A (0.45) | HIF1APPARDTHRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0644183-B1 | Process of producing N-alkylacetamides | SHIONOGI & CO (JP) | 1999-06-02 | — | — | EP | disclosed |
| US-5498792-A | Process of producing N-alkylacetamides | SHIONOGI & CO., LTD. (JP) | 1996-03-12 | — | — | US | disclosed |
| EP-0644183-A2 | Process of producing N-alkylacetamides | SHIONOGI & CO., LTD. (JP) | 1995-03-22 | — | — | EP | disclosed |