Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | F9 | P00740 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.33 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8396213 | 0.93 | SMN1; SMN2 (0.39) | SMN1; SMN2HTTLMNAALDH1A1MAPT | |
| SCHEMBL8399605 | 0.91 | LTB4R2 (0.39) | HTTLMNAALDH1A1MAPTPAX8 | |
| SCHEMBL8398979 | 0.90 | SMN1; SMN2 (0.41) | SMN1; SMN2LMNAALDH1A1MAPTMEN1 | |
| SCHEMBL8395834 | 0.90 | SMN1; SMN2 (0.41) | SMN1; SMN2HTTLMNAALDH1A1MAPT | |
| SCHEMBL8396237 | 0.90 | SMN1; SMN2 (0.40) | SMN1; SMN2ALDH1A1MAPTMAOBAKR1B1 | |
| SCHEMBL8395289 | 0.89 | SMN1; SMN2 (0.40) | SMN1; SMN2LMNAALDH1A1MAPTMEN1 | |
| SCHEMBL8397061 | 0.89 | SMN1; SMN2 (0.40) | SMN1; SMN2LMNAALDH1A1MAPTMEN1 | |
| SCHEMBL8399202 | 0.88 | SMN1; SMN2 (0.52) | SMN1; SMN2HTTLMNAALDH1A1MAPT | |
| SCHEMBL8398120 | 0.88 | SMN1; SMN2 (0.39) | SMN1; SMN2AKR1B1 | |
| SCHEMBL8396256 | 0.87 | SMN1; SMN2 (0.39) | SMN1; SMN2LMNAALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647636-B1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | SENJU PHARMA CO (JP) | 1999-06-09 | — | — | EP | disclosed |
| US-5532257-A | ENZYME INHIBITOR | SENJU PHARMACEUTICAL CO., LTD (JP) | 1996-07-02 | — | — | US | disclosed |
| EP-0647636-A1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Senju Pharmaceutical Co., Ltd. (JP) | 1995-04-12 | — | — | EP | disclosed |