Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 6/20 | 0.58 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.58 |
| ▸ | ESR1 | P03372 | 2/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | ALPL | P05186 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | THPO | P40225 | 2/20 | 0.49 |
| ▸ | BLM | P54132 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8400498 | 1.00 | EGFR (0.58) | EGFRERBB2ESR1ESR2MAPT | |
| SCHEMBL8397484 | 0.87 | EGFR (0.62) | EGFRERBB2ESR1ESR2MAPT | |
| SCHEMBL249607 | 0.85 | ESR1 (0.69) | EGFRERBB2ESR1ESR2MAPT | |
| SCHEMBL8400486 | 0.84 | ESR1 (0.56) | EGFRERBB2ESR1ESR2MAPT | |
| SCHEMBL9241983 | 0.84 | ESR1 (0.56) | EGFRERBB2ESR1ESR2MAPT | |
| SCHEMBL8401367 | 0.84 | EGFR (0.58) | EGFRERBB2ESR1ESR2MAPT | |
| SCHEMBL8398968 | 0.84 | ESR1 (0.56) | EGFRERBB2ESR1ESR2MAPT | |
| SCHEMBL8398971 | 0.84 | ESR1 (0.56) | EGFRERBB2ESR1ESR2MAPT | |
| SCHEMBL8400487 | 0.84 | ESR1 (0.56) | EGFRERBB2ESR1ESR2MAPT | |
| SCHEMBL8401369 | 0.84 | EGFR (0.58) | EGFRERBB2ESR1ESR2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640586-B1 | STILBENE DERIVATIVE AND STILBENE ANALOG DERIVATIVE, AND USE THEREOF | MORINAGA MILK INDUSTRY CO LTD (JP) | 1999-06-09 | — | — | EP | disclosed |
| US-5589506-A | ENZYME INHIBITORS FOR LIPOXYGENASE | MORINAGA MILK INDUSTRY CO., LTD. (JP) | 1996-12-31 | — | — | US | disclosed |
| EP-0640586-A1 | STILBENE DERIVATIVE AND STILBENE ANALOG DERIVATIVE, AND USE THEREOF | MORINAGA MILK INDUSTRY CO., LTD. (JP) | 1995-03-01 | — | — | EP | disclosed |