SCHEMBL8400669

SCHEMBL8400669

Nc1ccc(Cc2ccc(N)c(S(=O)(=O)O)c2)cc1S(=O)(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 4/20 0.50
KDM4E B2RXH2 3/20 0.50
MAPT P10636 3/20 0.50
POLB P06746 2/20 0.50
MEN1 O00255 2/20 0.50
RAB9A P51151 2/20 0.50
KMT2A Q03164 2/20 0.50
ALDH1A1 P00352 6/20 0.48
CDC25B P30305 3/20 0.48
CASP6 P55212 2/20 0.48
RCE1 Q9Y256 1/20 0.48
RECQL P46063 2/20 0.45
CYP3A4 P08684 2/20 0.45
ESR2 Q92731 1/20 0.45
CTDSP1 Q9GZU7 1/20 0.44
HSD17B10 Q99714 4/20 0.43
HPGD P15428 2/20 0.43
ALOX15 P16050 2/20 0.43
TSHR P16473 2/20 0.43
TTR P02766 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL7547968 0.98 GAA (0.48) GAAKDM4EMAPTPOLBMEN1
Trimethylammonium SCHEMBL7550558 0.93 POLB (0.44) GAAKDM4EMAPTPOLBMEN1
SCHEMBL13071938 0.90 POLB (0.59) GAAKDM4EMAPTPOLBMEN1
SCHEMBL7550164 0.88 CTDSP1 (0.44) GAAKDM4EMAPTPOLBMEN1
SCHEMBL8074965 0.86 CTDSP1 (0.43) GAAKDM4EMAPTPOLBMEN1
SCHEMBL9167498 0.85 CTDSP1 (0.42) GAAKDM4EMAPTPOLBMEN1
SCHEMBL8747645 0.85 CTDSP1 (0.49) GAAKDM4EMAPTPOLBMEN1
SCHEMBL28152890 0.85 CTDSP1 (0.42) GAAKDM4EMAPTPOLBMEN1
SCHEMBL4649732 0.84 CTDSP1 (0.46) GAAKDM4EMAPTPOLBMEN1
SCHEMBL7550180 0.83 MAPT (0.42) GAAKDM4EMAPTPOLBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5859182-A Fluorine-containing polyquinazolone polymer and separation membrane using the same NITTO DENKO CORPORATION (JP) 1999-01-12 US disclosed
US-5290908-A Acetylenic end-capped polyimides THE UNIVERSITY OF NOTRE DAME DU LAC (US) 1994-03-01 US disclosed
US-4537947-A Chain-extending functional polyimides by dipole reactions UNIVERSITY OF NOTRE DAME DU LAC (US) 1985-08-27 US disclosed
US-4529793-A Selective permeable membranes comprising a polyquinazolone-based polymer NITTO ELECTRIC INDUSTRIAL CO., LTD. (JP) 1985-07-16 US disclosed
US-4528373-A Vinylacetylene-terminated polyimide derivatives PLASTICS ENGINEERING COMPANY (US) 1985-07-09 US disclosed
US-4528349-A Polymerization products of vinylacetylene-terminated polyimide derivatives PLASTICS ENGINEERING COMPANY (US) 1985-07-09 US disclosed
US-4520198-A A DIEL-ALDER ADDITION PRODUCT WITH DIENOPHILE PLASTICS ENGINEERING COMPANY (US) 1985-05-28 US disclosed
US-4517363-A Vinylacetylene-terminated polyimide derivatives PLASTICS ENGINEERING COMPANY (US) 1985-05-14 US disclosed
US-4517354-A PROTECTIVE COATINGS PLASTICS ENGINEERING COMPANY (US) 1985-05-14 US disclosed
US-4517364-A CROSSLINKING POYLMERS, DIELS-ALDER ADDITION REACTION PLASTICS ENGINEERING COMPANY (US) 1985-05-14 US disclosed
US-4060515-A Chain-extending nitrile end-capped polyimides UNIVERSITY OF NOTRE DAME DU LAC (US) 1977-11-29 US disclosed
US-4058505-A Chain-extending amine end-capped polyimides UNIVERSITY OF NOTRE DAME DU LAC (US) 1977-11-15 US disclosed
US-4055543-A Chain-extending Schiff base terminated polyimides and method of preparation ALELIO GAETANO FRANCIS D 1977-10-25 US disclosed
US-4026871-A Chain-extending phenolic end-capped polyimides UNIVERSITY OF NOTRE DAME (US) 1977-05-31 US disclosed
US-4026833-A CROSSLINKED FOAMS UNIVERSITY OF NOTRE DAME (US) 1977-05-31 US disclosed
US-4026904-A Aromatic epoxy-terminated polyimides UNIVERSITY OF NOTRE DAME (US) 1977-05-31 US disclosed
US-3998786-A USEFUL FOR PREPARING COATINGS UNIVERSITY OF NOTRE DAME DU LAC (US) 1976-12-21 US disclosed
US-3996196-A Polyimide-metallo-phthalocyanines and their preparation UNIVERSITY OF NOTRE DAME DU LAC (US) 1976-12-07 US disclosed
US-3987003-A THERMALLY STABLE DIOXO AND DITHIO-BENZISOQUINOLINE COMPOSITIONS AND PROCESS OF SYNTHESIZING SAME THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 1976-10-19 US disclosed
US-3960980-A Method of producing elastomer resins BRIDGESTONE TIRE COMPANY LIMITED (JA) 1976-06-01 US disclosed