Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8519257 | 0.80 | CHRM2 (0.37) | CHRM2 | |
| SCHEMBL8400243 | 0.74 | CHRM2 (0.36) | CHRM2CHRM3 | |
| SCHEMBL8400767 | 0.66 | CHRM2 (0.37) | CHRM2CHRM3 | |
| SCHEMBL8400245 | 0.63 | CHRM2 (0.68) | CHRM2CHRM3 | |
| SCHEMBL4790510 | 0.61 | NISCH (0.39) | — | |
| SCHEMBL46305 | 0.54 | CCR1 (0.52) | PPARA | |
| SCHEMBL5844 | 0.54 | SMN1; SMN2 (0.42) | PPARA | |
| SCHEMBL2644715 | 0.54 | SMN1; SMN2 (0.46) | PPARA | |
| SCHEMBL23033807 | 0.54 | — | — | |
| SCHEMBL23576574 | 0.53 | EPHX2 (0.41) | PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE36374-E | 1,2,3-triazole and tetrazole substituted piperidine or tetrahydropyridine compounds useful as acetylcholine agonists | H. LUNDBECK, A/S (DK) | 1999-11-02 | — | — | US | disclosed |
| EP-0296721-B1 | HETEROCYCLIC COMPOUNDS | H. LUNDBECK A/S (DK) | 1993-06-23 | — | — | EP | disclosed |
| US-4925858-A | NERVOUS SYSTEM DISORDERS, ALZHEIMER*S DISEASE | H. LUNDBECK A/S (DK) | 1990-05-15 | — | — | US | disclosed |
| US-4866077-A | TREATMENT OF NERVOUS SYSTEM DISORDERS SUCH AS ALZHEIMER*S DISEASE | H. LUNDBECK A/S (DK) | 1989-09-12 | — | — | US | disclosed |
| EP-0296721-A2 | Heterocyclic compounds | H. LUNDBECK A/S (DK) | 1988-12-28 | — | — | EP | disclosed |