Spermidine

Spermidine

SCHEMBL8401062

C/C=C\CC1CC(=O)CC1CC(=O)O.NCCCCNCCCN

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PAOX Q6QHF9 1/20 0.38
CA12 O43570 2/20 0.34
F13A1 P00488 2/20 0.34
CA2 P00918 2/20 0.34
CYP1A2 P05177 2/20 0.34
ALOX15 P16050 2/20 0.34
CA4 P22748 2/20 0.34
CA6 P23280 2/20 0.34
CA5A P35218 2/20 0.34
THPO P40225 2/20 0.34
CA7 P43166 2/20 0.34
CA9 Q16790 2/20 0.34
CA14 Q9ULX7 2/20 0.34
CA5B Q9Y2D0 2/20 0.34
CA1 P00915 1/20 0.34
CA3 P07451 1/20 0.34
CYP2C9 P11712 1/20 0.34
PKM P14618 1/20 0.34
TSHR P16473 1/20 0.34
MTOR P42345 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylamine SCHEMBL15638660 0.84 AKR1C4 (0.40) AKR1C4AKR1C3AKR1C2SLC6A12SLC6A11
Ammonia Solution, Strong SCHEMBL15571353 0.83 AKR1C4 (0.40) AKR1C4AKR1C3AKR1C2SLC6A12SLC6A11
Bromide SCHEMBL3200051 0.83 AKR1C4 (0.40) AKR1C4AKR1C3AKR1C2SLC6A12SLC6A11
SCHEMBL7826841 0.73 FNTA (0.31) CA2CA1AKR1C4AKR1C3AKR1C2
SCHEMBL16714096 0.73 HTT (0.33) LMNAAKR1C4AKR1C3AKR1C2
SCHEMBL1614931 0.72 AKR1C4 (0.33) AKR1C4AKR1C3AKR1C2
SCHEMBL36185 0.72 BRD4 (0.42) TSHRHDAC6KMT2A
SCHEMBL11810354 0.72 BRD4 (0.42) TSHRHDAC6KMT2A
SCHEMBL273492 0.72 BRD4 (0.42) TSHRHDAC6KMT2A
Bromide SCHEMBL895882 0.71 BRD4 (0.41) TSHRKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5968789-A CULTURING TISSUES OR CELLS OF PLANT FROM GENUS TAXUS IN NUTRIENT MEDIUM AND IN CONTACT WITH GAS HAVING OXYGEN AND 0.1 TO 5% CARBON DIOXIDE, RECOVERING COMPOUND FROM CULTURE MITSUI CHEMICALS, LTD. (JP) 1999-10-19 US disclosed
US-5637484-A CULTURING TISSUES OR CELLS OF PLANT BELONGING TO GENUS TAXUS IN PRESENCE OF JASMONIC ACID, RECOVERING TAXANE MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1997-06-10 US disclosed